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PROTAC, E3 Ligands & Proximity-Inducing Building Blocks

HQ461

HQ461

Produkt-Nr.CH57011CAS-Nr.1226443-41-9
HQ461

Produktübersicht

Kurzüberblick

Produktfamilie
PROTAC, E3 Ligands & Proximity-Inducing Building Blocks
Chemischer Name
HQ461
MF
C15H15N5OS2
MW
345.4

HQ461 is a thiazole-containing acetamide compound identified by CAS 1226443-41-9.

The verified record matches molecular formula C15H15N5OS2, molecular weight about 345.4, PubChem CID 49677967, and InChIKey QMRBCNQCRMTXBE-UHFFFAOYSA-N.

Published literature places HQ461 in molecular-glue research involving CDK12-DDB1 interaction and cyclin K degradation; the identifiers below keep that context tied to the confirmed compound identity.

Identität und Spezifikationen

Catalog No.CH57011
CAS No.1226443-41-9
Chemical NameHQ461
Molecular FormulaC15H15N5OS2
Molecular Weight345.4
PubChem CID49677967
IUPAC Name2-[2-[(6-methyl-2-pyridinyl)amino]-1,3-thiazol-4-yl]-N-(5-methyl-1,3-thiazol-2-yl)acetamide
SynonymsHQ-461; HQ 461; CHEMBL5175040
InChIKeyQMRBCNQCRMTXBE-UHFFFAOYSA-N

Anwendungskontext

  • CDK12-DDB1 research: published records discuss HQ461 in molecular-glue research involving CDK12-DDB1 interaction.
  • Cyclin K research background: literature records associate HQ461 with cyclin K degradation research.
  • Catalog data alignment: helps keep CAS 1226443-41-9, formula C15H15N5OS2, PubChem CID 49677967, and InChIKey QMRBCNQCRMTXBE-UHFFFAOYSA-N consistent across records.

Weitere Materialinformationen

Eigenschaften

  • Thiazole-containing acetamide structure with a methylpyridinyl amino substituent.
  • Nitrogen- and sulfur-containing heteroaromatic compound with formula C15H15N5OS2.
  • CAS and name lookups both resolve to PubChem CID 49677967.

Zugehörige technische Ressourcen

PROTAC / TPD Bausteine

CRBN/VHL-Derivate, Ligand-Linker, bifunktionale Intermediate und Linker-Bausteine.

PROTAC-Linker-Auswahl

Serien aus beiden Liganden, Exit-Vektoren, ternärer Geometrie, Konformation, Permeabilität, Synthese und Assays entwerfen.

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