CHEMOS
SMCC crosslinker

SMCC crosslinker

Nombre químico

(2,5-dioxopyrrolidin-1-yl) 4-[(2,5-dioxopyrrol-1-yl)methyl]cyclohexane-1-carboxylate

SMCC crosslinker•ADC linker
Structure: SMCC crosslinker structure, CAS 64987-85-5, MW 334.32
N.º de producto
CH53015
CAS
64987-85-5
FM
C16H18N2O6
PM
334.32
Especificación
Catalog No.CH53015
CAS No.64987-85-5
Molecular FormulaC16H18N2O6
Molecular Weight334.32

CHEMOS Support for This Category

CHEMOS supports ADC linker and bioconjugation building-block projects from route design through custom synthesis and process optimization. Custom linker synthesis : peptide, PEG, self-immolative, cleavable, and non-cleavable linker structures. Functional-handle installation : NHS ester, maleimide, azide, alkyne, and other conjugation-ready groups. Multi-step route development : protecting-group strategy, coupling optimization, purification review, and impurity-profile control. Analytical support : HPLC, NMR, MS, and chiral methods where applicable. Scale-up planning : laboratory-to-production transfer can be evaluated after route feasibility and specification review.

Descripción general

SMCC crosslinker (also known as (2,5-dioxopyrrolidin-1-yl) 4-[(2,5-dioxopyrrol-1-yl)methyl]cyclohexane-1-carboxylate) (CAS 64987-85-5, MF C16H18N2O6, MW 334.32) is used as a linker / reactive-handle building block in ADC and bioconjugation research. Programs working with this compound usually examine selectivity of the bioconjugation chemistry, linker stability, and downstream payload release. Custom synthesis, process scale-up and supply planning are available through CHEMOS R&D and manufacturing facilities.

Aplicaciones

  • SMCC crosslinker (CAS 64987-85-5) route review and custom analog preparation
  • Cleavable peptide-linker design and intracellular-release studies
  • Click-chemistry coupling (DBCO / azide) for bioconjugation programs
  • Custom linker / payload-linker synthesis on request

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