DOTA-NHS-ester
DOTA-NHS-ester
Resumen del producto
Vista rápida
- Familia de productos
- ADC Linkers & Conjugation Reagents
- Nombre químico
- DOTA-NHS-ester
- FM
- C20H31N5O10
- PM
- 501.5
DOTA-NHS-ester is a DOTA-family NHS ester identified by CAS 170908-81-3.
This record matches molecular formula C20H31N5O10, molecular weight about 501.5, and PubChem CID 11488945.
Use the DOTA-NHS-ester name with CAS 170908-81-3 when comparing catalog and external database records.
Identidad y especificaciones
| Catalog No. | CH53020 |
| CAS No. | 170908-81-3 |
| Chemical Name | DOTA-NHS-ester |
| Molecular Formula | C20H31N5O10 |
| Molecular Weight | 501.5 |
| PubChem CID | 11488945 |
Contexto de aplicación
- DOTA NHS ester identity reference: supports matching DOTA-NHS-ester with CAS 170908-81-3 and PubChem CID 11488945.
- DOTA-conjugate research: supporting literature places DOTA NHS ester chemistry in DOTA-conjugate research records.
- Identifier alignment: useful when formula, molecular weight, CAS number, and PubChem identity need to be checked together.
Información adicional del material
Usos
Useful for aligning DOTA-NHS-ester with CAS 170908-81-3, formula C20H31N5O10, molecular weight about 501.5, and PubChem CID 11488945.
Características
- DOTA-family compound with an NHS ester identity.
- CAS and product-name lookups both resolve to PubChem CID 11488945.
- This page represents the product as a DOTA-chelator identity rather than generic category wording.
Recursos técnicos relacionados
Química de enlazadores y cargas para ADC
Enlazadores escindibles o estables, espaciadores hidrofílicos, grupos reactivos selectivos e intermedios carga-enlazador.
Enlazadores ADC escindibles y no escindibles
Comparación según la especie liberada, el mecanismo de activación, la estabilidad en circulación, el procesamiento celular, la carga molecular, la conjugación y la evidencia analítica.
Fuentes públicas
- Tetraxetan N-hydroxysuccinimide | PubChem CID 11488945
- Development of Solid-Phase Site-Specific Conjugation and Its Application toward Generation of Dual Labeled Antibody and Fab Drug Conjugates
Bioconjugate Chemistry, 2016
Product-family technical context
- Effect of Linker-Drug Properties and Conjugation Site on the Physical Stability of ADCs
Journal of Pharmaceutical Sciences, 2020
Product-family technical context
- Antibody-Maytansinoid Conjugates Are Activated in Targeted Cancer Cells by Lysosomal Degradation and Linker-Dependent Intracellular Processing
Cancer Research, 2006
Product-family technical context
- The Effect of Different Linkers on Target Cell Catabolism and Pharmacokinetics/Pharmacodynamics of Trastuzumab Maytansinoid Conjugates
Molecular Cancer Therapeutics, 2012
Product-family technical context
Preguntas frecuentes
Which research appears in the references?
Supporting references include DOTA-conjugate research; this page keeps the product identity tied to CAS 170908-81-3 and PubChem CID 11488945.
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