Maleimide-NOTA

Maleimide-NOTA

화학명

2-[4-(carboxymethyl)-7-[2-[2-(2,5-dioxopyrrol-1-yl)ethylamino]-2-oxoethyl]-1,4,7-triazonan-1-yl]acetic acid

Maleimide-NOTANOTA
Structure: Maleimide-NOTA structure, CAS 1295584-83-6, MW 425.44
제품 번호
CH55002
CAS
1295584-83-6
분자식
C18H27N5O7
분자량
425.44
사양
Catalog No.CH55002
CAS No.1295584-83-6
Molecular FormulaC18H27N5O7
Molecular Weight425.44

CHEMOS Support for This Category

CHEMOS supports NOTA, NODAGA, and related chelator building-block projects for research and development use. NOTA-family derivatives : protected, activated, and pre-conjugated variants for downstream chemistry. Custom conjugate intermediates : chelator-linker and chelator-linker-peptide building blocks. Trace-metal awareness : process and analytical planning for radiolabeling-sensitive intermediates. Moisture-sensitive handling : packaging and handling requirements can be reviewed by compound form. Technical documentation : batch-specific COA and supporting technical information are provided according to confirmed specification.

개요

Maleimide-NOTA (also known as 2-[4-(carboxymethyl)-7-[2-[2-(2,5-dioxopyrrol-1-yl)ethylamino]-2-oxoethyl]-1,4,7-triazonan-1-yl]acetic acid) (CAS 1295584-83-6, MF C18H27N5O7, MW 425.44) is a NOTA / NODAGA-family macrocyclic chelator building block used in ⁶⁸Ga and ⁶⁴Cu PET tracer research. Practical chemistry topics include rapid radiometal complexation, conjugation handle chemistry, and analytical control of metal-binding stability. Project scale-up and custom synthesis are coordinated by the CHEMOS R&D team across laboratory and production sites.

응용

  • Maleimide-NOTA (1295584-83-6) as a starting point for downstream chemistry programs
  • Trace-metal control studies for PET tracer chemistry
  • Rapid radiometal complexation studies for short-half-life isotopes
  • Custom synthesis of mono-functionalised NOTA / NODAGA derivatives

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