Azetidin-3-ol hydrochloride
Chemical Name
azetidin-3-ol;hydrochloride
Azetidin-3-ol hydrochloride•ADC linker
Structure: 
Product No
CH53010
CAS
18621-18-6
MF
C3H8ClNO
MW
109.55
Specification
| Catalog No. | CH53010 |
| CAS No. | 18621-18-6 |
| Molecular Formula | C3H8ClNO |
| Molecular Weight | 109.55 |
CHEMOS Support for This Category
CHEMOS supports ADC linker and bioconjugation building-block projects from route design through custom synthesis and process optimization. Custom linker synthesis : peptide, PEG, self-immolative, cleavable, and non-cleavable linker structures. Functional-handle installation : NHS ester, maleimide, azide, alkyne, and other conjugation-ready groups. Multi-step route development : protecting-group strategy, coupling optimization, purification review, and impurity-profile control. Analytical support : HPLC, NMR, MS, and chiral methods where applicable. Scale-up planning : laboratory-to-production transfer can be evaluated after route feasibility and specification review.
Overview
Azetidin-3-ol hydrochloride (also known as azetidin-3-ol;hydrochloride) (CAS 18621-18-6, MF C3H8ClNO, MW 109.55) is used as a linker / reactive-handle building block in ADC and bioconjugation research. Programs working with this compound usually examine selectivity of the bioconjugation chemistry, linker stability, and downstream payload release. Bench-scale to larger-scale production is supported through CHEMOS organic chemistry workflows and dedicated process-development resources.
Applications
- Azetidin-3-ol hydrochloride (18621-18-6) as a starting point for downstream chemistry programs
- Process-development support for scalable linker preparation
- Bioconjugation handle for site-specific cysteine / lysine attachment
- Click-chemistry coupling (DBCO / azide) for bioconjugation programs
Need Custom Synthesis?
Our CDMO team provides end-to-end custom synthesis support from discovery through process development and scale-up.
Explore CDMO Services