CHEMOS
AEEA-AEEA

AEEA-AEEA

Chemical Name

2-[2-[2-[[2-[2-(2-aminoethoxy)ethoxy]acetyl]amino]ethoxy]ethoxy]acetic acid

AEEA-AEEA•ADC linker
Structure: AEEA-AEEA structure, CAS 1143516-05-5, MW 308.33
Product No
CH53013
CAS
1143516-05-5
MF
C12H24N2O7
MW
308.33
Specification
Catalog No.CH53013
CAS No.1143516-05-5
Molecular FormulaC12H24N2O7
Molecular Weight308.33

CHEMOS Support for This Category

CHEMOS supports ADC linker and bioconjugation building-block projects from route design through custom synthesis and process optimization. Custom linker synthesis : peptide, PEG, self-immolative, cleavable, and non-cleavable linker structures. Functional-handle installation : NHS ester, maleimide, azide, alkyne, and other conjugation-ready groups. Multi-step route development : protecting-group strategy, coupling optimization, purification review, and impurity-profile control. Analytical support : HPLC, NMR, MS, and chiral methods where applicable. Scale-up planning : laboratory-to-production transfer can be evaluated after route feasibility and specification review.

Overview

AEEA-AEEA (also known as 2-[2-[2-[[2-[2-(2-aminoethoxy)ethoxy]acetyl]amino]ethoxy]ethoxy]acetic acid) (CAS 1143516-05-5, MF C12H24N2O7, MW 308.33) is used as a linker / reactive-handle building block in ADC and bioconjugation research. Programs working with this compound usually examine selectivity of the bioconjugation chemistry, linker stability, and downstream payload release. CHEMOS process-development team and large production base can support route refinement, scale-up and custom synthesis on request.

Applications

  • AEEA-AEEA (CAS 1143516-05-5) route review and custom analog preparation
  • Cleavable peptide-linker design and intracellular-release studies
  • Custom linker / payload-linker synthesis on request
  • Antibody-drug conjugate (ADC) linker chemistry research

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