Succinic anhydride
Chemical Name
oxolane-2,5-dione
Succinic anhydride•ADC linker
Structure: 
Product No
CH53014
CAS
108-30-5
MF
C4H4O3
MW
100.07
Specification
| Catalog No. | CH53014 |
| CAS No. | 108-30-5 |
| Molecular Formula | C4H4O3 |
| Molecular Weight | 100.07 |
CHEMOS Support for This Category
CHEMOS supports ADC linker and bioconjugation building-block projects from route design through custom synthesis and process optimization. Custom linker synthesis : peptide, PEG, self-immolative, cleavable, and non-cleavable linker structures. Functional-handle installation : NHS ester, maleimide, azide, alkyne, and other conjugation-ready groups. Multi-step route development : protecting-group strategy, coupling optimization, purification review, and impurity-profile control. Analytical support : HPLC, NMR, MS, and chiral methods where applicable. Scale-up planning : laboratory-to-production transfer can be evaluated after route feasibility and specification review.
Overview
Succinic anhydride (also known as oxolane-2,5-dione) (CAS 108-30-5, MF C4H4O3, MW 100.07) is an antibody-drug conjugate (ADC) linker or bioconjugation building block. Chemistry topics around such compounds typically cover the reactive handle (maleimide / NHS / DBCO / azide), linker stability in plasma, and release behaviour intracellularly. CHEMOS process-development team and large production base can support route refinement, scale-up and custom synthesis on request.
Applications
- Succinic anhydride (CAS 108-30-5) preparation, route refinement, and analytical-control planning
- Bioconjugation handle for site-specific cysteine / lysine attachment
- Click-chemistry coupling (DBCO / azide) for bioconjugation programs
- Process-development support for scalable linker preparation
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