CHEMOS
Sulfo-SMCC sodium

Sulfo-SMCC sodium

Chemical Name

sodium 1-[4-[(2,5-dioxopyrrol-1-yl)methyl]cyclohexanecarbonyl]oxy-2,5-dioxopyrrolidine-3-sulfonate

Sulfo-SMCC sodium•ADC linker
Structure: Sulfo-SMCC sodium structure, CAS 92921-24-9, MW 438.38
Product No
CH53019
CAS
92921-24-9
MF
C16H17N2NaO9S
MW
438.38
Specification
Catalog No.CH53019
CAS No.92921-24-9
Molecular FormulaC16H17N2NaO9S
Molecular Weight438.38

CHEMOS Support for This Category

CHEMOS supports ADC linker and bioconjugation building-block projects from route design through custom synthesis and process optimization. Custom linker synthesis : peptide, PEG, self-immolative, cleavable, and non-cleavable linker structures. Functional-handle installation : NHS ester, maleimide, azide, alkyne, and other conjugation-ready groups. Multi-step route development : protecting-group strategy, coupling optimization, purification review, and impurity-profile control. Analytical support : HPLC, NMR, MS, and chiral methods where applicable. Scale-up planning : laboratory-to-production transfer can be evaluated after route feasibility and specification review.

Overview

Sulfo-SMCC sodium (also known as sodium 1-[4-[(2,5-dioxopyrrol-1-yl)methyl]cyclohexanecarbonyl]oxy-2,5-dioxopyrrolidine-3-sulfonate) (CAS 92921-24-9, MF C16H17N2NaO9S, MW 438.38) belongs to the ADC linker / bioconjugation handle class. Practical chemistry questions involve the conjugation chemistry, peptide-cleavable element design (where applicable), and analytical control of related impurities. CHEMOS process chemistry, organic synthesis routes and project scale-up support are offered for downstream programs.

Applications

  • Sulfo-SMCC sodium (92921-24-9) supply and analog preparation for research programs
  • Click-chemistry coupling (DBCO / azide) for bioconjugation programs
  • Process-development support for scalable linker preparation
  • Bioconjugation handle for site-specific cysteine / lysine attachment

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