CHEMOS
NH-CH2-CH2-DOTAM

NH-CH2-CH2-DOTAM

NH-CH2-CH2-DOTAM•DOTA
Structure: NH-CH2-CH2-DOTAM structure, CAS 2685840-60-0, MW 443.55
Product No
CH54015
CAS
2685840-60-0
MW
443.55
Specification
Catalog No.CH54015
CAS No.2685840-60-0
Molecular Weight443.55

CHEMOS Support for This Category

CHEMOS supports DOTA chelator and radiopharmaceutical building-block chemistry, including protected, activated, PEG-spaced, and conjugation-ready intermediates. DOTA and DOTA-GA derivatives : protected chelators, activated esters, maleimide derivatives, and linker-spaced variants. Custom chelator-linker synthesis : route design for chelator-linker-targeting moiety intermediates. Metal-sensitive process control : purification and analytical planning for low-metal-background requirements. Analytical support : HPLC, NMR, MS, and ICP-MS can be discussed according to project needs. Scale-up support : process optimization and batch-size planning after technical review.

Overview

NH-CH2-CH2-DOTAM (CAS 2685840-60-0, MW 443.55) is part of the DOTA chelator family used in targeted radioligand and imaging-conjugate research. Practical chemistry topics include mono-functionalisation of the macrocycle, protection-group strategy, and conjugation chemistry with peptides or antibodies. Custom synthesis, process scale-up and supply planning are available through CHEMOS R&D and manufacturing facilities.

Applications

  • NH-CH2-CH2-DOTAM (CAS 2685840-60-0) preparation, route refinement, and analytical-control planning
  • Custom synthesis of mono-functionalised DOTA derivatives
  • Process-development support for scalable chelator preparation
  • Trace-metal control studies for radiopharmaceutical conjugates

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