CHEMOS
BCN-DOTA-GA

BCN-DOTA-GA

Chemical Name

5-[2-[[(1S,8R)-9-bicyclo[6.1.0]non-4-ynyl]methoxycarbonylamino]ethylamino]-5-oxo-2-[4,7,10-tris(carboxymethyl)-1,4,7,10-tetrazacyclododec-1-yl]pentanoic acid

BCN-DOTA-GA•DOTA
Structure: BCN-DOTA-GA structure, CAS 2416980-98-6, MW 694.77
Product No
CH54018
CAS
2416980-98-6
MF
C32H50N6O11
MW
694.77
Specification
Catalog No.CH54018
CAS No.2416980-98-6
Molecular FormulaC32H50N6O11
Molecular Weight694.77

CHEMOS Support for This Category

CHEMOS supports DOTA chelator and radiopharmaceutical building-block chemistry, including protected, activated, PEG-spaced, and conjugation-ready intermediates. DOTA and DOTA-GA derivatives : protected chelators, activated esters, maleimide derivatives, and linker-spaced variants. Custom chelator-linker synthesis : route design for chelator-linker-targeting moiety intermediates. Metal-sensitive process control : purification and analytical planning for low-metal-background requirements. Analytical support : HPLC, NMR, MS, and ICP-MS can be discussed according to project needs. Scale-up support : process optimization and batch-size planning after technical review.

Overview

BCN-DOTA-GA (also known as 5-[2-[[(1S,8R)-9-bicyclo[6.1.0]non-4-ynyl]methoxycarbonylamino]ethylamino]-5-oxo-2-[4,7,10-tris(carboxymethyl)-1,4,7,10-tetrazacyclododec-1-yl]pentanoic acid) (CAS 2416980-98-6, MF C32H50N6O11, MW 694.77) belongs to the DOTA-family chelator class for targeted radiopharmaceutical research. Programs typically examine residual metal control, kinetic inertness of the metal complex, and the available coupling handle. CHEMOS process-development team and large production base can support route refinement, scale-up and custom synthesis on request.

Applications

  • BCN-DOTA-GA (2416980-98-6) supply and analog preparation for research programs
  • Process-development support for scalable chelator preparation
  • Trace-metal control studies for radiopharmaceutical conjugates
  • Targeted radioligand therapy (TRT) building block — ⁹⁰Y / ¹⁷⁷Lu / ²²⁵Ac conjugates

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