Maleimide-NOTA
Chemical Name
2-[4-(carboxymethyl)-7-[2-[2-(2,5-dioxopyrrol-1-yl)ethylamino]-2-oxoethyl]-1,4,7-triazonan-1-yl]acetic acid
Maleimide-NOTA•NOTA
Structure: 
Product No
CH55002
CAS
1295584-83-6
MF
C18H27N5O7
MW
425.44
Specification
| Catalog No. | CH55002 |
| CAS No. | 1295584-83-6 |
| Molecular Formula | C18H27N5O7 |
| Molecular Weight | 425.44 |
CHEMOS Support for This Category
CHEMOS supports NOTA, NODAGA, and related chelator building-block projects for research and development use. NOTA-family derivatives : protected, activated, and pre-conjugated variants for downstream chemistry. Custom conjugate intermediates : chelator-linker and chelator-linker-peptide building blocks. Trace-metal awareness : process and analytical planning for radiolabeling-sensitive intermediates. Moisture-sensitive handling : packaging and handling requirements can be reviewed by compound form. Technical documentation : batch-specific COA and supporting technical information are provided according to confirmed specification.
Overview
Maleimide-NOTA (also known as 2-[4-(carboxymethyl)-7-[2-[2-(2,5-dioxopyrrol-1-yl)ethylamino]-2-oxoethyl]-1,4,7-triazonan-1-yl]acetic acid) (CAS 1295584-83-6, MF C18H27N5O7, MW 425.44) is a NOTA / NODAGA-family macrocyclic chelator building block used in ⁶⁸Ga and ⁶⁴Cu PET tracer research. Practical chemistry topics include rapid radiometal complexation, conjugation handle chemistry, and analytical control of metal-binding stability. Project scale-up and custom synthesis are coordinated by the CHEMOS R&D team across laboratory and production sites.
Applications
- Maleimide-NOTA (1295584-83-6) as a starting point for downstream chemistry programs
- Trace-metal control studies for PET tracer chemistry
- Rapid radiometal complexation studies for short-half-life isotopes
- Custom synthesis of mono-functionalised NOTA / NODAGA derivatives
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