p-SCN-Bn-NOTA trihydrochloride
Chemical Name
2,2',2''-(2-(4-isothiocyanatobenzyl)-1,4,7-triazonane-1,4,7-triyl)triacetic acid trihydrochloride
p-SCN-Bn-NOTA trihydrochloride•NOTA
Structure: 
Product No
CH55004
CAS
1583289-85-3
MF
C20H29Cl3N4O6S
MW
559.89
Specification
| Catalog No. | CH55004 |
| CAS No. | 1583289-85-3 |
| Molecular Formula | C20H29Cl3N4O6S |
| Molecular Weight | 559.89 |
CHEMOS Support for This Category
CHEMOS supports NOTA, NODAGA, and related chelator building-block projects for research and development use. NOTA-family derivatives : protected, activated, and pre-conjugated variants for downstream chemistry. Custom conjugate intermediates : chelator-linker and chelator-linker-peptide building blocks. Trace-metal awareness : process and analytical planning for radiolabeling-sensitive intermediates. Moisture-sensitive handling : packaging and handling requirements can be reviewed by compound form. Technical documentation : batch-specific COA and supporting technical information are provided according to confirmed specification.
Overview
p-SCN-Bn-NOTA trihydrochloride (also known as 2,2',2''-(2-(4-isothiocyanatobenzyl)-1,4,7-triazonane-1,4,7-triyl)triacetic acid trihydrochloride) (CAS 1583289-85-3, MF C20H29Cl3N4O6S, MW 559.89) is a NOTA / NODAGA-family macrocyclic chelator building block used in ⁶⁸Ga and ⁶⁴Cu PET tracer research. Practical chemistry topics include rapid radiometal complexation, conjugation handle chemistry, and analytical control of metal-binding stability. Custom synthesis, process scale-up and supply planning are available through CHEMOS R&D and manufacturing facilities.
Applications
- p-SCN-Bn-NOTA trihydrochloride (1583289-85-3) supply and analog preparation for research programs
- Rapid radiometal complexation studies for short-half-life isotopes
- Peptide-NOTA / NODAGA conjugate synthesis (somatostatin, PSMA, FAPI etc.)
- Custom synthesis of mono-functionalised NOTA / NODAGA derivatives
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