NOTA-bis(tBu)ester
Chemical Name
2-[4,7-bis[2-[(2-methylpropan-2-yl)oxy]-2-oxoethyl]-1,4,7-triazonan-1-yl]acetic acid
NOTA-bis(tBu)ester•NOTA
Structure: 
Product No
CH55005
CAS
1161415-28-6
MF
C20H37N3O6
MW
415.52
Specification
| Catalog No. | CH55005 |
| CAS No. | 1161415-28-6 |
| Molecular Formula | C20H37N3O6 |
| Molecular Weight | 415.52 |
CHEMOS Support for This Category
CHEMOS supports NOTA, NODAGA, and related chelator building-block projects for research and development use. NOTA-family derivatives : protected, activated, and pre-conjugated variants for downstream chemistry. Custom conjugate intermediates : chelator-linker and chelator-linker-peptide building blocks. Trace-metal awareness : process and analytical planning for radiolabeling-sensitive intermediates. Moisture-sensitive handling : packaging and handling requirements can be reviewed by compound form. Technical documentation : batch-specific COA and supporting technical information are provided according to confirmed specification.
Overview
NOTA-bis(tBu)ester (also known as 2-[4,7-bis[2-[(2-methylpropan-2-yl)oxy]-2-oxoethyl]-1,4,7-triazonan-1-yl]acetic acid) (CAS 1161415-28-6, MF C20H37N3O6, MW 415.52) is part of the NOTA / NODAGA chelator class used in PET tracer development. Programs working with this compound typically focus on selective ring functionalisation, residual metal control, and conjugate compatibility with biomolecules. Bench-scale to larger-scale production is supported through CHEMOS organic chemistry workflows and dedicated process-development resources.
Applications
- NOTA-bis(tBu)ester (1161415-28-6) as a starting point for downstream chemistry programs
- Trace-metal control studies for PET tracer chemistry
- PET tracer chemistry — ⁶⁸Ga and ⁶⁴Cu radiopharmaceutical building block
- Rapid radiometal complexation studies for short-half-life isotopes
Need Custom Synthesis?
Our CDMO team provides end-to-end custom synthesis support from discovery through process development and scale-up.
Explore CDMO Services