CHEMOS
p-NCS-Bz-NODA-GA

p-NCS-Bz-NODA-GA

Chemical Name

2-[4,7-bis(carboxymethyl)-1,4,7-triazonan-1-yl]-5-[(4-isothiocyanatophenyl)methylamino]-5-oxopentanoic acid

p-NCS-Bz-NODA-GA•NOTA
Structure: p-NCS-Bz-NODA-GA structure, CAS 1660127-21-8, MW 521.59
Product No
CH55007
CAS
1660127-21-8
MF
C23H31N5O7S
MW
521.59
Specification
Catalog No.CH55007
CAS No.1660127-21-8
Molecular FormulaC23H31N5O7S
Molecular Weight521.59

CHEMOS Support for This Category

CHEMOS supports NOTA, NODAGA, and related chelator building-block projects for research and development use. NOTA-family derivatives : protected, activated, and pre-conjugated variants for downstream chemistry. Custom conjugate intermediates : chelator-linker and chelator-linker-peptide building blocks. Trace-metal awareness : process and analytical planning for radiolabeling-sensitive intermediates. Moisture-sensitive handling : packaging and handling requirements can be reviewed by compound form. Technical documentation : batch-specific COA and supporting technical information are provided according to confirmed specification.

Overview

p-NCS-Bz-NODA-GA (also known as 2-[4,7-bis(carboxymethyl)-1,4,7-triazonan-1-yl]-5-[(4-isothiocyanatophenyl)methylamino]-5-oxopentanoic acid) (CAS 1660127-21-8, MF C23H31N5O7S, MW 521.59) is a NOTA / NODAGA-family macrocyclic chelator building block used in ⁶⁸Ga and ⁶⁴Cu PET tracer research. Practical chemistry topics include rapid radiometal complexation, conjugation handle chemistry, and analytical control of metal-binding stability. Project scale-up and custom synthesis are coordinated by the CHEMOS R&D team across laboratory and production sites.

Applications

  • p-NCS-Bz-NODA-GA (1660127-21-8) as a starting point for downstream chemistry programs
  • Trace-metal control studies for PET tracer chemistry
  • PET tracer chemistry — ⁶⁸Ga and ⁶⁴Cu radiopharmaceutical building block
  • Rapid radiometal complexation studies for short-half-life isotopes

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