CHEMOS
NO2A-Butyne-bis(t-Butyl ester)

NO2A-Butyne-bis(t-Butyl ester)

Chemical Name

tert-butyl 2-[4-[2-(but-3-ynylamino)-2-oxoethyl]-7-[2-[(2-methylpropan-2-yl)oxy]-2-oxoethyl]-1,4,7-triazonan-1-yl]acetate

NO2A-Butyne-bis(t-Butyl ester)•NOTA
Structure: NO2A-Butyne-bis(t-Butyl ester) structure, CAS 2125661-91-6, MW 466.62
Product No
CH55015
CAS
2125661-91-6
MF
C24H42N4O5
MW
466.62
Specification
Catalog No.CH55015
CAS No.2125661-91-6
Molecular FormulaC24H42N4O5
Molecular Weight466.62

CHEMOS Support for This Category

CHEMOS supports NOTA, NODAGA, and related chelator building-block projects for research and development use. NOTA-family derivatives : protected, activated, and pre-conjugated variants for downstream chemistry. Custom conjugate intermediates : chelator-linker and chelator-linker-peptide building blocks. Trace-metal awareness : process and analytical planning for radiolabeling-sensitive intermediates. Moisture-sensitive handling : packaging and handling requirements can be reviewed by compound form. Technical documentation : batch-specific COA and supporting technical information are provided according to confirmed specification.

Overview

NO2A-Butyne-bis(t-Butyl ester) (also known as tert-butyl 2-[4-[2-(but-3-ynylamino)-2-oxoethyl]-7-[2-[(2-methylpropan-2-yl)oxy]-2-oxoethyl]-1,4,7-triazonan-1-yl]acetate) (CAS 2125661-91-6, MF C24H42N4O5, MW 466.62) belongs to the NOTA / NODAGA macrocyclic chelator family used in radiopharmaceutical research. Typical chemistry questions involve protection-group strategy, mono-functionalisation, and conjugation chemistry for peptide or antibody coupling. Project scale-up and custom synthesis are coordinated by the CHEMOS R&D team across laboratory and production sites.

Applications

  • NO2A-Butyne-bis(t-Butyl ester) (CAS 2125661-91-6) route review and custom analog preparation
  • Trace-metal control studies for PET tracer chemistry
  • Rapid radiometal complexation studies for short-half-life isotopes
  • Custom synthesis of mono-functionalised NOTA / NODAGA derivatives

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