NO2A-(t-Bu ester)

NO2A-(t-Bu ester)

Chemical Name

tert-butyl 2-[4-[2-[(2-methylpropan-2-yl)oxy]-2-oxoethyl]-1,4,7-triazonan-1-yl]acetate

NO2A-(t-Bu ester)NOTA
Structure: NO2A-(t-Bu ester) structure, CAS 174137-97-4, MW 357.49
Product No
CH55020
CAS
174137-97-4
MF
C18H35N3O4
MW
357.49
Specification
Catalog No.CH55020
CAS No.174137-97-4
Molecular FormulaC18H35N3O4
Molecular Weight357.49

CHEMOS Support for This Category

CHEMOS supports NOTA, NODAGA, and related chelator building-block projects for research and development use. NOTA-family derivatives : protected, activated, and pre-conjugated variants for downstream chemistry. Custom conjugate intermediates : chelator-linker and chelator-linker-peptide building blocks. Trace-metal awareness : process and analytical planning for radiolabeling-sensitive intermediates. Moisture-sensitive handling : packaging and handling requirements can be reviewed by compound form. Technical documentation : batch-specific COA and supporting technical information are provided according to confirmed specification.

Overview

NO2A-(t-Bu ester) (also known as tert-butyl 2-[4-[2-[(2-methylpropan-2-yl)oxy]-2-oxoethyl]-1,4,7-triazonan-1-yl]acetate) (CAS 174137-97-4, MF C18H35N3O4, MW 357.49) belongs to the NOTA / NODAGA macrocyclic chelator family used in radiopharmaceutical research. Typical chemistry questions involve protection-group strategy, mono-functionalisation, and conjugation chemistry for peptide or antibody coupling. CHEMOS process-development team and large production base can support route refinement, scale-up and custom synthesis on request.

Applications

  • NO2A-(t-Bu ester) (174137-97-4) as a starting point for downstream chemistry programs
  • Rapid radiometal complexation studies for short-half-life isotopes
  • Custom synthesis of mono-functionalised NOTA / NODAGA derivatives
  • Trace-metal control studies for PET tracer chemistry

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