NOTA trihydrochloride
NOTA trihydrochloride•NOTA
Structure: 
Product No
CH55022
CAS
133256-65-2
MW
339.77
Specification
| Catalog No. | CH55022 |
| CAS No. | 133256-65-2 |
| Molecular Weight | 339.77 |
CHEMOS Support for This Category
CHEMOS supports NOTA, NODAGA, and related chelator building-block projects for research and development use. NOTA-family derivatives : protected, activated, and pre-conjugated variants for downstream chemistry. Custom conjugate intermediates : chelator-linker and chelator-linker-peptide building blocks. Trace-metal awareness : process and analytical planning for radiolabeling-sensitive intermediates. Moisture-sensitive handling : packaging and handling requirements can be reviewed by compound form. Technical documentation : batch-specific COA and supporting technical information are provided according to confirmed specification.
Overview
NOTA trihydrochloride (CAS 133256-65-2, MW 339.77) belongs to the NOTA / NODAGA macrocyclic chelator family used in radiopharmaceutical research. Typical chemistry questions involve protection-group strategy, mono-functionalisation, and conjugation chemistry for peptide or antibody coupling. Bench-scale to larger-scale production is supported through CHEMOS organic chemistry workflows and dedicated process-development resources.
Applications
- NOTA trihydrochloride (133256-65-2) as a starting point for downstream chemistry programs
- Process-development support for scalable chelator preparation
- PET tracer chemistry — ⁶⁸Ga and ⁶⁴Cu radiopharmaceutical building block
- Peptide-NOTA / NODAGA conjugate synthesis (somatostatin, PSMA, FAPI etc.)
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