NOTA-FAPI
化学名称
2-[4-(carboxymethyl)-7-[2-[4-[3-[4-[[2-[(2S)-2-cyano-4,4-difluoropyrrolidin-1-yl]-2-oxoethyl]carbamoyl]quinolin-6-yl]oxypropyl]piperazin-1-yl]-2-oxoethyl]-1,4,7-triazonan-1-yl]acetic acid
NOTA-FAPI•NOTA
Structure: 
产品编号
CH55006
CAS
2374782-03-1
分子式
C36H47F2N9O8
分子量
771.82
规格标准
| Catalog No. | CH55006 |
| CAS No. | 2374782-03-1 |
| Molecular Formula | C36H47F2N9O8 |
| Molecular Weight | 771.82 |
品类工艺支持
CHEMOS supports NOTA, NODAGA, and related chelator building-block projects for research and development use. NOTA-family derivatives : protected, activated, and pre-conjugated variants for downstream chemistry. Custom conjugate intermediates : chelator-linker and chelator-linker-peptide building blocks. Trace-metal awareness : process and analytical planning for radiolabeling-sensitive intermediates. Moisture-sensitive handling : packaging and handling requirements can be reviewed by compound form. Technical documentation : batch-specific COA and supporting technical information are provided according to confirmed specification.
概况
NOTA-FAPI (also known as 2-[4-(carboxymethyl)-7-[2-[4-[3-[4-[[2-[(2S)-2-cyano-4,4-difluoropyrrolidin-1-yl]-2-oxoethyl]carbamoyl]quinolin-6-yl]oxypropyl]piperazin-1-yl]-2-oxoethyl]-1,4,7-triazonan-1-yl]acetic acid) (CAS 2374782-03-1, MF C36H47F2N9O8, MW 771.82) is a NOTA / NODAGA-family macrocyclic chelator building block used in ⁶⁸Ga and ⁶⁴Cu PET tracer research. Practical chemistry topics include rapid radiometal complexation, conjugation handle chemistry, and analytical control of metal-binding stability. CHEMOS process chemistry, organic synthesis routes and project scale-up support are offered for downstream programs.
应用
- NOTA-FAPI (CAS 2374782-03-1) preparation, route refinement, and analytical-control planning
- Process-development support for scalable chelator preparation
- Trace-metal control studies for PET tracer chemistry
- PET tracer chemistry — ⁶⁸Ga and ⁶⁴Cu radiopharmaceutical building block