NOPO
化学名称
3-[[4,7-bis[[hydroxy(hydroxymethyl)phosphoryl]methyl]-1,4,7-triazonan-1-yl]methyl-hydroxyphosphoryl]propanoic acid
NOPO•NOTA
Structure: 
产品编号
CH55011
CAS
1397275-76-1
分子式
C14H32N3O10P3
分子量
495.34
规格标准
| Catalog No. | CH55011 |
| CAS No. | 1397275-76-1 |
| Molecular Formula | C14H32N3O10P3 |
| Molecular Weight | 495.34 |
品类工艺支持
CHEMOS supports NOTA, NODAGA, and related chelator building-block projects for research and development use. NOTA-family derivatives : protected, activated, and pre-conjugated variants for downstream chemistry. Custom conjugate intermediates : chelator-linker and chelator-linker-peptide building blocks. Trace-metal awareness : process and analytical planning for radiolabeling-sensitive intermediates. Moisture-sensitive handling : packaging and handling requirements can be reviewed by compound form. Technical documentation : batch-specific COA and supporting technical information are provided according to confirmed specification.
概况
NOPO (also known as 3-[[4,7-bis[[hydroxy(hydroxymethyl)phosphoryl]methyl]-1,4,7-triazonan-1-yl]methyl-hydroxyphosphoryl]propanoic acid) (CAS 1397275-76-1, MF C14H32N3O10P3, MW 495.34) is part of the NOTA / NODAGA chelator class used in PET tracer development. Programs working with this compound typically focus on selective ring functionalisation, residual metal control, and conjugate compatibility with biomolecules. CHEMOS process-development team and large production base can support route refinement, scale-up and custom synthesis on request.
应用
- NOPO (1397275-76-1) as a starting point for downstream chemistry programs
- Rapid radiometal complexation studies for short-half-life isotopes
- Peptide-NOTA / NODAGA conjugate synthesis (somatostatin, PSMA, FAPI etc.)
- Custom synthesis of mono-functionalised NOTA / NODAGA derivatives