NODAGA-NHS

NODAGA-NHS

化学名称

2-[4,7-bis(carboxymethyl)-1,4,7-triazonan-1-yl]-5-(2,5-dioxopyrrolidin-1-yl)oxy-5-oxopentanoic acid

NODAGA-NHSNOTA
Structure: NODAGA-NHS structure, CAS 1407166-70-4, MW 472.45
产品编号
CH55013
CAS
1407166-70-4
分子式
C19H28N4O10
分子量
472.45
规格标准
Catalog No.CH55013
CAS No.1407166-70-4
Molecular FormulaC19H28N4O10
Molecular Weight472.45

品类工艺支持

CHEMOS supports NOTA, NODAGA, and related chelator building-block projects for research and development use. NOTA-family derivatives : protected, activated, and pre-conjugated variants for downstream chemistry. Custom conjugate intermediates : chelator-linker and chelator-linker-peptide building blocks. Trace-metal awareness : process and analytical planning for radiolabeling-sensitive intermediates. Moisture-sensitive handling : packaging and handling requirements can be reviewed by compound form. Technical documentation : batch-specific COA and supporting technical information are provided according to confirmed specification.

概况

NODAGA-NHS (also known as 2-[4,7-bis(carboxymethyl)-1,4,7-triazonan-1-yl]-5-(2,5-dioxopyrrolidin-1-yl)oxy-5-oxopentanoic acid) (CAS 1407166-70-4, MF C19H28N4O10, MW 472.45) is part of the NOTA / NODAGA chelator class used in PET tracer development. Programs working with this compound typically focus on selective ring functionalisation, residual metal control, and conjugate compatibility with biomolecules. Project scale-up and custom synthesis are coordinated by the CHEMOS R&D team across laboratory and production sites.

应用

  • NODAGA-NHS (CAS 1407166-70-4) preparation, route refinement, and analytical-control planning
  • Process-development support for scalable chelator preparation
  • Trace-metal control studies for PET tracer chemistry
  • PET tracer chemistry — ⁶⁸Ga and ⁶⁴Cu radiopharmaceutical building block

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