Boc-β-Ala-OH
化学名称
3-[(tert-butoxycarbonyl)amino]propanoic acid
Boc-β-Ala-OH•PROTAC
Structure: 
产品编号
CH56017
CAS
3303-84-2
分子式
C8H15NO4
分子量
189.21
规格标准
| Catalog No. | CH56017 |
| CAS No. | 3303-84-2 |
| Molecular Formula | C8H15NO4 |
| Molecular Weight | 189.21 |
品类工艺支持
CHEMOS supports PROTAC building-block projects covering linkers, E3 ligase recruiter derivatives, and customized degrader intermediates. Linker building blocks : PEG acids, PEG azides, alkyl spacers, branched linkers, and rigid linkers. E3 recruiter derivatives : IMiD-related, VHL-related, and other recruiter building blocks for medicinal chemistry programs. Custom synthesis : linker design, functional-group installation, and intermediate preparation. Route and purification review : multi-step synthesis planning with attention to polarity, solubility, and impurity control. Scale-up evaluation : larger-batch preparation can be assessed after route feasibility review.
概况
Boc-β-Ala-OH (also known as 3-[(tert-butoxycarbonyl)amino]propanoic acid) (CAS 3303-84-2, MF C8H15NO4, MW 189.21) is used as a PROTAC research building block in degrader chemistry. Typical chemistry questions involve route design for the bifunctional architecture, linker selection, and analytical control of residual reagents. CHEMOS process-development team and large production base can support route refinement, scale-up and custom synthesis on request.
应用
- Boc-β-Ala-OH (CAS 3303-84-2) preparation, route refinement, and analytical-control planning
- Reference material in targeted protein degradation chemistry programs
- PROTAC building block — linker / E3-ligand / degrader handle
- Bifunctional degrader synthesis with orthogonal protecting groups