2'-Deoxyadenosine Monohydrate
(2R,3S,5R)-5-(6-aminopurin-9-yl)-2-(hydroxymethyl)oxolan-3-ol;hydrate
Produktübersicht
Kurzüberblick
- Produktfamilie
- Oligonucleotide Synthesis, RNA Raw Materials & Modification
- Chemischer Name
- (2R,3S,5R)-5-(6-aminopurin-9-yl)-2-(hydroxymethyl)oxolan-3-ol;hydrate
- MF
- C10H15N5O4
- MW
- 269.26
- Reinheit
- 100%
2'-Deoxyadenosine monohydrate is the hydrated dAdo form of the purine DNA nucleoside, with adenine linked to 2-deoxy-β-D-ribose. CH64001 is identified by CAS 16373-93-6, molecular formula C10H15N5O4, molecular weight 269.26, and PubChem CID 9549172.
Keep this record separate from anhydrous 2'-deoxyadenosine, which is listed separately as CH64007. In research literature, 2'-deoxyadenosine appears as a deoxynucleoside-kinase substrate and as the natural dA reference in polymerase and nucleoside-chemistry studies.
Synonyme
2'-Deoxyadenosine monohydrate; dAdo monohydrate; 2'-deoxyriboadenosine hydrate
Identität und Spezifikationen
| Catalog No. | CH64001 |
| CAS No. | 16373-93-6 |
| Molecular Formula | C10H15N5O4 (monohydrate) |
| Molecular Weight | 269.26 (monohydrate) |
| PubChem CID | 9549172 |
| InChIKey | WZJWHIMNXWKNTO-VWZUFWLJSA-N |
| Purity | 100% |
Lagerbedingungen
2-8 C
Technische Merkmale
- Nucleobase
- Adenine
- Sugar
- 2'-Deoxyribose
- Nucleoside class
- Purine 2'-deoxyribonucleoside
- Material form
- Monohydrate
- Packaging
- Custom packaging on request
- Water content
- 5-7.5%
- Physical form
- White to almost white crystal to powder
Anwendungskontext
- Kinase phosphorylation research: literature reports 2'-deoxyadenosine as a substrate for deoxycytidine kinase and adenosine kinase.
- Polymerase building-block studies: modified dA building blocks are compared against the natural deoxyribonucleoside scaffold during polymerase-incorporation research.
- Nucleoside chemistry reference: the hydrated dAdo record provides a defined 2'-deoxyribonucleoside identity for DNA and oligonucleotide chemistry work.
Zugehörige technische Ressourcen
Öffentliche Quellen
- Sustainability Challenges and Opportunities in Oligonucleotide Manufacturing
Journal of Organic Chemistry, 2021
Product-family technical context
- Solid-phase supports for oligonucleotide synthesis
Current Protocols in Nucleic Acid Chemistry, 2013
Product-family technical context
- Deoxynucleoside phosphoramidites—A new class of key intermediates for deoxypolynucleotide synthesis
Tetrahedron Letters, 1981
Product-family technical context
- Synthesis of deoxyoligonucleotides on a polymer support
Journal of the American Chemical Society, 1981
Product-family technical context
- PubChem-Verbindung 9549172
PubChem · CID 9549172
Häufig gestellte Fragen
Is CH64001 the monohydrate or anhydrous form?
It is the monohydrate (CAS 16373-93-6, C10H15N5O4, MW 269.26). The anhydrous 2'-deoxyadenosine (CAS 958-09-8) is listed as a separate CHEMOS product.
How is 2'-deoxyadenosine used as a kinase substrate?
It is phosphorylated by deoxycytidine kinase and adenosine kinase, so it is used as a defined purine deoxynucleoside substrate in kinase phosphorylation research.
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