2'-Deoxycytidine
4-amino-1-[(2R,4S,5R)-4-hydroxy-5-(hydroxymethyl)oxolan-2-yl]pyrimidin-2-one
Produktübersicht
Kurzüberblick
- Produktfamilie
- Oligonucleotide Synthesis, RNA Raw Materials & Modification
- Chemischer Name
- 4-amino-1-[(2R,4S,5R)-4-hydroxy-5-(hydroxymethyl)oxolan-2-yl]pyrimidin-2-one
- MF
- C9H13N3O4
- MW
- 227.22
- Reinheit
- 100.00% (HPLC)
2'-Deoxycytidine is the pyrimidine DNA nucleoside formed from cytosine and 2-deoxy-β-D-ribose. CH64002 is listed under CAS 951-77-9, molecular formula C9H13N3O4, molecular weight 227.22, and PubChem CID 13711; dCyd is a common shorthand for the same nucleoside.
This record is distinct from cytidine, the corresponding RNA nucleoside. In research literature, deoxycytidine appears as a deoxycytidine-kinase substrate and as the parent dC scaffold behind 5-methyl-deoxycytidine used in DNA-methylation studies.
Synonyme
2'-Deoxycytidine; deoxycytidine; dCyd; 2'-deoxyribocytidine
Identität und Spezifikationen
| Catalog No. | CH64002 |
| CAS No. | 951-77-9 |
| Molecular Formula | C9H13N3O4 |
| Molecular Weight | 227.22 |
| PubChem CID | 13711 |
| InChIKey | CKTSBUTUHBMZGZ-SHYZEUOFSA-N |
| Purity | 100.00% (HPLC) |
Lagerbedingungen
4 C; hygroscopic
Technische Merkmale
- Nucleobase
- Cytosine
- Sugar
- 2'-Deoxyribose
- Nucleoside class
- Pyrimidine 2'-deoxyribonucleoside
- Packaging
- Custom packaging on request
- Water content
- <=8%
- Physical form
- White crystalline powder
- Stability
- Tested 2022-02-17; retest 2029-02-15
Anwendungskontext
- Kinase phosphorylation research: deoxycytidine is reported as a substrate of deoxycytidine kinase in deoxyribonucleoside salvage-pathway studies.
- DNA-methylation studies: 5-methyl-deoxycytidine nucleotides derived from the dC scaffold are used in methylation-focused DNA research.
- Pyrimidine DNA nucleoside reference: CH64002 provides the canonical dC identity for nucleoside and oligonucleotide chemistry comparisons.
Zugehörige technische Ressourcen
Öffentliche Quellen
- Sustainability Challenges and Opportunities in Oligonucleotide Manufacturing
Journal of Organic Chemistry, 2021
Product-family technical context
- Solid-phase supports for oligonucleotide synthesis
Current Protocols in Nucleic Acid Chemistry, 2013
Product-family technical context
- Deoxynucleoside phosphoramidites—A new class of key intermediates for deoxypolynucleotide synthesis
Tetrahedron Letters, 1981
Product-family technical context
- Synthesis of deoxyoligonucleotides on a polymer support
Journal of the American Chemical Society, 1981
Product-family technical context
- PubChem-Verbindung 13711
PubChem · CID 13711
Häufig gestellte Fragen
Is CH64002 the DNA or RNA nucleoside?
It is 2'-deoxycytidine, the DNA (2'-deoxyribo) nucleoside. The RNA counterpart, cytidine, is listed separately by CHEMOS.
Why is deoxycytidine used in kinase research?
It is the defining substrate of deoxycytidine kinase in the nucleoside salvage pathway, so it serves as a reference pyrimidine deoxynucleoside in phosphorylation studies.
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