2'-Deoxyguanosine Monohydrate
2-amino-9-[(2R,4S,5R)-4-hydroxy-5-(hydroxymethyl)oxolan-2-yl]-1H-purin-6-one;hydrate
Produktübersicht
Kurzüberblick
- Produktfamilie
- Oligonucleotide Synthesis, RNA Raw Materials & Modification
- Chemischer Name
- 2-amino-9-[(2R,4S,5R)-4-hydroxy-5-(hydroxymethyl)oxolan-2-yl]-1H-purin-6-one;hydrate
- MF
- C10H15N5O5
- MW
- 285.26
- Reinheit
- 99.4% (HPLC)
2'-Deoxyguanosine monohydrate is the hydrated dGuo form of the purine DNA nucleoside, with guanine linked to 2-deoxy-β-D-ribose. CH64003 is listed under CAS 312693-72-4, molecular formula C10H15N5O5, molecular weight 285.26, and PubChem CID 135445705.
Keep this monohydrate record separate from anhydrous 2'-deoxyguanosine, which is cataloged separately as CH64008. In nucleoside research, deoxyguanosine is used as a deoxyguanosine-kinase substrate and as the canonical dG reference for purine DNA nucleoside chemistry.
Synonyme
2'-Deoxyguanosine monohydrate; dGuo monohydrate; 2'-deoxyriboguanosine hydrate
Identität und Spezifikationen
| Catalog No. | CH64003 |
| CAS No. | 312693-72-4 |
| Molecular Formula | C10H15N5O5 (monohydrate) |
| Molecular Weight | 285.26 (monohydrate) |
| PubChem CID | 135445705 |
| InChIKey | LZSCQUCOIRGCEJ-FPKZOZHISA-N |
| Purity | 99.4% (HPLC) |
Lagerbedingungen
-20 C
Technische Merkmale
- Nucleobase
- Guanine
- Sugar
- 2'-Deoxyribose
- Nucleoside class
- Purine 2'-deoxyribonucleoside
- Material form
- Monohydrate
- Packaging
- Custom packaging on request
- Water content
- Karl Fischer 6.1% w/w
- Physical form
- Solid
- Stability
- >=4 years
Anwendungskontext
- Salvage-pathway phosphorylation research: literature reports deoxyguanosine as a substrate of deoxyguanosine kinase (dGK).
- Purine DNA nucleoside reference: CH64003 provides the monohydrate dG identity for nucleoside and oligonucleotide chemistry comparisons.
Zugehörige technische Ressourcen
Öffentliche Quellen
- Sustainability Challenges and Opportunities in Oligonucleotide Manufacturing
Journal of Organic Chemistry, 2021
Product-family technical context
- Solid-phase supports for oligonucleotide synthesis
Current Protocols in Nucleic Acid Chemistry, 2013
Product-family technical context
- Deoxynucleoside phosphoramidites—A new class of key intermediates for deoxypolynucleotide synthesis
Tetrahedron Letters, 1981
Product-family technical context
- Synthesis of deoxyoligonucleotides on a polymer support
Journal of the American Chemical Society, 1981
Product-family technical context
- PubChem-Verbindung 135445705
PubChem · CID 135445705
Häufig gestellte Fragen
Is CH64003 the monohydrate or anhydrous form?
It is the monohydrate (CAS 312693-72-4, C10H15N5O5, MW 285.26). The anhydrous 2'-deoxyguanosine (CAS 961-07-9) is listed as a separate CHEMOS product.
How is deoxyguanosine used in kinase research?
It is phosphorylated by deoxyguanosine kinase (dGK) in the nucleoside salvage pathway, so it serves as a defined purine deoxynucleoside substrate in phosphorylation studies.
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