2'-Deoxyadenosine (anhydrous)
(2R,3S,5R)-5-(6-aminopurin-9-yl)-2-(hydroxymethyl)oxolan-3-ol
Produktübersicht
Kurzüberblick
- Produktfamilie
- Oligonucleotide Synthesis, RNA Raw Materials & Modification
- Chemischer Name
- (2R,3S,5R)-5-(6-aminopurin-9-yl)-2-(hydroxymethyl)oxolan-3-ol
- MF
- C10H13N5O3
- MW
- 251.24
- Reinheit
- >98.0% (HPLC, titration)
2'-Deoxyadenosine is the anhydrous dAdo form of the purine DNA nucleoside, with adenine linked to 2-deoxy-β-D-ribose. CH64007 is identified by CAS 958-09-8, molecular formula C10H13N5O3, molecular weight 251.24, and PubChem CID 13730.
Keep this record separate from 2'-deoxyadenosine monohydrate, which is listed separately as CH64001. In research literature, 2'-deoxyadenosine appears as a deoxynucleoside-kinase substrate and as the natural dA reference in polymerase and nucleoside-chemistry studies.
Synonyme
2'-Deoxyadenosine; deoxyadenosine; dAdo; dA (nucleoside)
Identität und Spezifikationen
| Catalog No. | CH64007 |
| CAS No. | 958-09-8 |
| Molecular Formula | C10H13N5O3 (anhydrous) |
| Molecular Weight | 251.24 (anhydrous) |
| PubChem CID | 13730 |
| InChIKey | OLXZPDWKRNYJJZ-RRKCRQDMSA-N |
| Purity | >98.0% (HPLC, titration) |
Lagerbedingungen
0-10 C
Technische Merkmale
- Nucleobase
- Adenine
- Sugar
- 2'-Deoxyribose
- Nucleoside class
- Purine 2'-deoxyribonucleoside
- Material form
- Anhydrous
- Packaging
- Custom packaging on request
- Physical form
- Solid; white to almost white powder to crystal
Anwendungskontext
- Kinase phosphorylation research: literature reports 2'-deoxyadenosine as a substrate for deoxycytidine kinase and adenosine kinase.
- Polymerase building-block studies: modified dA building blocks are compared against the natural deoxyribonucleoside scaffold during polymerase-incorporation research.
- Purine DNA nucleoside reference: CH64007 provides the anhydrous dAdo identity for nucleoside and oligonucleotide chemistry comparisons.
Zugehörige technische Ressourcen
Öffentliche Quellen
- Sustainability Challenges and Opportunities in Oligonucleotide Manufacturing
Journal of Organic Chemistry, 2021
Product-family technical context
- Solid-phase supports for oligonucleotide synthesis
Current Protocols in Nucleic Acid Chemistry, 2013
Product-family technical context
- Deoxynucleoside phosphoramidites—A new class of key intermediates for deoxypolynucleotide synthesis
Tetrahedron Letters, 1981
Product-family technical context
- Synthesis of deoxyoligonucleotides on a polymer support
Journal of the American Chemical Society, 1981
Product-family technical context
- PubChem-Verbindung 13730
PubChem · CID 13730
Häufig gestellte Fragen
Is CH64007 the anhydrous or monohydrate form?
It is the anhydrous form (CAS 958-09-8, C10H13N5O3, MW 251.24). The monohydrate 2'-deoxyadenosine (CAS 16373-93-6) is listed as a separate CHEMOS product.
How is 2'-deoxyadenosine used as a kinase substrate?
It is phosphorylated by deoxycytidine kinase and adenosine kinase, so it is used as a defined purine deoxynucleoside substrate in phosphorylation research.
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