2'-Deoxyguanosine (anhydrous)
2-amino-9-[(2R,4S,5R)-4-hydroxy-5-(hydroxymethyl)oxolan-2-yl]-1H-purin-6-one
Produktübersicht
Kurzüberblick
- Produktfamilie
- Oligonucleotide Synthesis, RNA Raw Materials & Modification
- Chemischer Name
- 2-amino-9-[(2R,4S,5R)-4-hydroxy-5-(hydroxymethyl)oxolan-2-yl]-1H-purin-6-one
- MF
- C10H13N5O4
- MW
- 267.24
- Reinheit
- >99.0% (HPLC)
2'-Deoxyguanosine is the anhydrous dGuo form of the purine DNA nucleoside, with guanine linked to 2-deoxy-β-D-ribose. CH64008 is identified by CAS 961-07-9, molecular formula C10H13N5O4, molecular weight 267.24, and PubChem CID 135398592.
Keep this record separate from CH64003, the monohydrate 2'-deoxyguanosine entry. The supported use context is research-facing: dGuo appears as a deoxyguanosine-kinase substrate in salvage-phosphorylation studies and as a canonical purine 2'-deoxyribonucleoside reference in nucleoside chemistry.
Synonyme
2'-Deoxyguanosine; deoxyguanosine; dGuo; dG (nucleoside)
Identität und Spezifikationen
| Catalog No. | CH64008 |
| CAS No. | 961-07-9 |
| Molecular Formula | C10H13N5O4 (anhydrous) |
| Molecular Weight | 267.24 (anhydrous) |
| PubChem CID | 135398592 |
| InChIKey | YKBGVTZYEHREMT-KVQBGUIXSA-N |
| Purity | >99.0% (HPLC) |
Lagerbedingungen
Room temperature; cool and dark place below 15 C; inert gas
Technische Merkmale
- Nucleobase
- Guanine
- Sugar
- 2'-Deoxyribose
- Nucleoside class
- Purine 2'-deoxyribonucleoside
- Material form
- Anhydrous
- Packaging
- 1 g glass bottle with plastic insert; Custom packaging on request
- Water content
- <=10.0%
- Physical form
- Solid; white to almost white powder to crystal
Anwendungskontext
- Deoxyguanosine kinase substrate: dGuo is used as the defined purine deoxynucleoside substrate in deoxyguanosine-kinase salvage-phosphorylation research.
- Purine DNA nucleoside reference: CH64008 provides the anhydrous dGuo identity for nucleoside and oligonucleotide chemistry comparisons.
Zugehörige technische Ressourcen
Öffentliche Quellen
- Sustainability Challenges and Opportunities in Oligonucleotide Manufacturing
Journal of Organic Chemistry, 2021
Product-family technical context
- Solid-phase supports for oligonucleotide synthesis
Current Protocols in Nucleic Acid Chemistry, 2013
Product-family technical context
- Deoxynucleoside phosphoramidites—A new class of key intermediates for deoxypolynucleotide synthesis
Tetrahedron Letters, 1981
Product-family technical context
- Synthesis of deoxyoligonucleotides on a polymer support
Journal of the American Chemical Society, 1981
Product-family technical context
- PubChem-Verbindung 135398592
PubChem · CID 135398592
Häufig gestellte Fragen
Is CH64008 the anhydrous or monohydrate form?
It is the anhydrous form (CAS 961-07-9, C10H13N5O4, MW 267.24). The monohydrate 2'-deoxyguanosine (CAS 312693-72-4) is listed as a separate CHEMOS product.
How is deoxyguanosine used in kinase research?
It is phosphorylated by deoxyguanosine kinase (dGK) in the nucleoside salvage pathway, so it serves as a defined purine deoxynucleoside substrate in phosphorylation studies.
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