Inosine
9-[(2R,3R,4S,5R)-3,4-dihydroxy-5-(hydroxymethyl)oxolan-2-yl]-1H-purin-6-one
Produktübersicht
Kurzüberblick
- Produktfamilie
- Oligonucleotide Synthesis, RNA Raw Materials & Modification
- Chemischer Name
- 9-[(2R,3R,4S,5R)-3,4-dihydroxy-5-(hydroxymethyl)oxolan-2-yl]-1H-purin-6-one
- MF
- C10H12N4O5
- MW
- 268.23
- Reinheit
- 100.0% (HPLC)
Inosine is the purine RNA nucleoside with hypoxanthine linked to β-D-ribose. CH64013 is identified by CAS 58-63-9, molecular formula C10H12N4O5, molecular weight 268.23, and PubChem CID 135398641. It is the ribose counterpart of 2'-deoxyinosine, which is cataloged separately as CH64006.
The supported research context is PNP enzymology and RNA nucleoside chemistry: inosine is a purine nucleoside phosphorylase substrate and a hypoxanthine ribonucleoside reference.
Synonyme
Inosine; hypoxanthine riboside; Ino
Identität und Spezifikationen
| Catalog No. | CH64013 |
| CAS No. | 58-63-9 |
| Molecular Formula | C10H12N4O5 |
| Molecular Weight | 268.23 |
| PubChem CID | 135398641 |
| InChIKey | UGQMRVRMYYASKQ-KQYNXXCUSA-N |
| Purity | 100.0% (HPLC) |
Lagerbedingungen
-20 C
Technische Merkmale
- Nucleobase
- Hypoxanthine
- Sugar
- D-Ribose
- Nucleoside class
- Purine ribonucleoside
- Packaging
- Custom packaging on request
- Physical form
- Solid
- Stability
- >=4 years
Anwendungskontext
- Purine nucleoside phosphorylase substrate: inosine is used as a defined substrate in PNP structural and enzymology research.
- Purine RNA nucleoside reference: CH64013 provides the hypoxanthine ribonucleoside identity for RNA and nucleoside chemistry comparisons.
Zugehörige technische Ressourcen
Öffentliche Quellen
- Sustainability Challenges and Opportunities in Oligonucleotide Manufacturing
Journal of Organic Chemistry, 2021
Product-family technical context
- Solid-phase supports for oligonucleotide synthesis
Current Protocols in Nucleic Acid Chemistry, 2013
Product-family technical context
- Deoxynucleoside phosphoramidites—A new class of key intermediates for deoxypolynucleotide synthesis
Tetrahedron Letters, 1981
Product-family technical context
- Synthesis of deoxyoligonucleotides on a polymer support
Journal of the American Chemical Society, 1981
Product-family technical context
- PubChem-Verbindung 135398641
PubChem · CID 135398641
Häufig gestellte Fragen
Is CH64013 the RNA or DNA nucleoside?
It is inosine, the RNA (ribo) nucleoside. The DNA counterpart, 2'-deoxyinosine, is listed separately by CHEMOS.
How is inosine used in enzyme research?
Inosine is a substrate of purine nucleoside phosphorylase (PNP), which phosphorolyzes it to hypoxanthine and ribose-1-phosphate, so it serves as a reference substrate in PNP enzymology.
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