5-TFA-aa-2'-deoxyuridine
Oligonucleotide Synthesis, RNA Raw Materials & Modification
Produktübersicht
Kurzüberblick
- Produktfamilie
- Oligonucleotide Synthesis, RNA Raw Materials & Modification
- MF
- C14H16F3N3O6
- MW
- 379.29
- Reinheit
- 98%
5-TFA-aa-2'-deoxyuridine is 2'-deoxyuridine carrying an aminoallyl amino-linker at the C5 position of uracil, with the linker's terminal amine protected as a trifluoroacetamide (TFA). CH64058 is identified by CAS 115794-55-3, molecular formula C14H16F3N3O6, molecular weight 379.29, PubChem CID 10959831, and InChIKey MBPYSSRDTGXWJD-HFVMFMDWSA-N.
The aminoallyl arm provides a protected amine-linker motif on a 2'-deoxy nucleoside. The cited labeling literature discusses amine-linker nucleosides in covalent fluorophore attachment and indirect labeling research for nucleic acids.
Synonyme
5-(trifluoroacetamidoallyl)-2'-deoxyuridine; 5-TFA-aa-dU
Identität und Spezifikationen
| Catalog No. | CH64058 |
| CAS No. | 115794-55-3 |
| Molecular Formula | C14H16F3N3O6 |
| Molecular Weight | 379.29 |
| PubChem CID | 10959831 |
| InChIKey | MBPYSSRDTGXWJD-HFVMFMDWSA-N |
| Purity | 98% |
Technische Merkmale
- Nucleobase
- Uracil
- Sugar
- 2'-Deoxyribose
- C5 linker
- Aminoallyl
- Amine protection
- Trifluoroacetyl (TFA)
- Grade
- BR
- Packaging
- 100 mg; 250 mg; 500 mg; 1 g; Custom packaging on request
Anwendungskontext
- Aminoallyl labeling research: CH64058 combines a 2'-deoxyuridine identity with a C5 TFA-protected aminoallyl linker for indirect DNA and oligonucleotide labeling studies.
- Amine-linker labeling studies: the TFA-protected aminoallyl group represents a protected amine-linker motif discussed for covalent fluorophore attachment after deprotection.
- Base-analog reference: CH64058 provides the 5-TFA-aa-2'-deoxyuridine identity for nucleoside chemistry research.
Zugehörige technische Ressourcen
Öffentliche Quellen
- Sustainability Challenges and Opportunities in Oligonucleotide Manufacturing
Journal of Organic Chemistry, 2021
Product-family technical context
- Solid-phase supports for oligonucleotide synthesis
Current Protocols in Nucleic Acid Chemistry, 2013
Product-family technical context
- Deoxynucleoside phosphoramidites—A new class of key intermediates for deoxypolynucleotide synthesis
Tetrahedron Letters, 1981
Product-family technical context
- Synthesis of deoxyoligonucleotides on a polymer support
Journal of the American Chemical Society, 1981
Product-family technical context
- PubChem-Verbindung 10959831
PubChem · CID 10959831
Häufig gestellte Fragen
What does 'aa' (aminoallyl) mean here?
'aa' is the aminoallyl linker, a 3-aminoprop-1-enyl arm at C5. Its terminal amine is protected as a trifluoroacetamide (TFA).
How is it different from 5-TFA-aa-Uridine?
This is the 2'-deoxy (DNA) version; 5-TFA-aa-Uridine is the ribonucleoside (RNA) version. They are cataloged separately.
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