5-Iodo-2'-deoxyuridine
Oligonucleotide Synthesis, RNA Raw Materials & Modification
Produktübersicht
Kurzüberblick
- Produktfamilie
- Oligonucleotide Synthesis, RNA Raw Materials & Modification
- MF
- C9H11IN2O5
- MW
- 354.10
- Reinheit
- 99.6% (HPLC)
5-Iodo-2'-deoxyuridine (IUdR) is 2'-deoxyuridine bearing an iodine at the C5 position of uracil, making it a thymidine analog. CH64060 is identified by CAS 54-42-2, molecular formula C9H11IN2O5, molecular weight 354.10, PubChem CID 5905, and InChIKey XQFRJNBWHJMXHO-RRKCRQDMSA-N.
The cited literature reports IUdR as a thymidine analog incorporated into DNA of S-phase cells. CH64060 is framed as a halogenated-pyrimidine nucleoside for DNA-incorporation and modified-DNA research.
Identität und Spezifikationen
| Catalog No. | CH64060 |
| CAS No. | 54-42-2 |
| Molecular Formula | C9H11IN2O5 |
| Molecular Weight | 354.10 |
| PubChem CID | 5905 |
| InChIKey | XQFRJNBWHJMXHO-RRKCRQDMSA-N |
| Purity | 99.6% (HPLC) |
Lagerbedingungen
Room temperature; recommended cool and dark below 15 C
Technische Merkmale
- Nucleobase
- Uracil
- Sugar
- 2'-Deoxyribose
- Base substituent
- 5-Iodo
- Nucleoside class
- Halogenated pyrimidine deoxyribonucleoside
- Packaging
- 1 g; 5 g; 25 g; Custom packaging on request
- Water content
- 0.4% loss on drying (KF), lot result
- Physical form
- solid; white to almost white powder to crystal
- Stability
- >=4 years
Anwendungskontext
- S-phase DNA-incorporation research: the cited literature reports 5-iodo-2'-deoxyuridine as a thymidine analog incorporated into newly synthesized DNA in S-phase cells.
- Halogenated-pyrimidine studies: the C5 iodine supports modified-DNA base-analog research contexts.
- Base-analog reference: CH64060 provides the 5-iodo-2'-deoxyuridine identity for nucleoside chemistry research.
Zugehörige technische Ressourcen
Öffentliche Quellen
- Sustainability Challenges and Opportunities in Oligonucleotide Manufacturing
Journal of Organic Chemistry, 2021
Product-family technical context
- Solid-phase supports for oligonucleotide synthesis
Current Protocols in Nucleic Acid Chemistry, 2013
Product-family technical context
- Deoxynucleoside phosphoramidites—A new class of key intermediates for deoxypolynucleotide synthesis
Tetrahedron Letters, 1981
Product-family technical context
- Synthesis of deoxyoligonucleotides on a polymer support
Journal of the American Chemical Society, 1981
Product-family technical context
- PubChem-Verbindung 5905
PubChem · CID 5905
Häufig gestellte Fragen
How does it differ from 2'-deoxyuridine?
It carries an iodine at the C5 position of uracil (a heavy atom), whereas 2'-deoxyuridine is unsubstituted. 2'-deoxyuridine is cataloged separately.
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