8-Bromo-2'-deoxyadenosine
Oligonucleotide Synthesis, RNA Raw Materials & Modification
Produktübersicht
Kurzüberblick
- Produktfamilie
- Oligonucleotide Synthesis, RNA Raw Materials & Modification
- MF
- C10H12BrN5O3
- MW
- 330.14
- Reinheit
- >98% (HPLC)
8-Bromo-2'-deoxyadenosine is 2'-deoxyadenosine bearing a bromine at the C8 position of adenine. CH64067 is identified by CAS 14985-44-5, molecular formula C10H12BrN5O3, molecular weight 330.14, PubChem CID 96547, and InChIKey NJBIVXMQFIQOGE-KVQBGUIXSA-N.
The cited literature discusses 8-substituted purine nucleosides and nucleotides in relation to syn/anti glycosidic conformation. CH64067 provides the 8-bromo-2'-deoxyadenosine identity for modified-DNA, base-analog, and C8-functionalization research contexts.
Synonyme
8-Bromo-2'-deoxyadenosine; 8-Br-dA
Identität und Spezifikationen
| Catalog No. | CH64067 |
| CAS No. | 14985-44-5 |
| Molecular Formula | C10H12BrN5O3 |
| Molecular Weight | 330.14 |
| PubChem CID | 96547 |
| InChIKey | NJBIVXMQFIQOGE-KVQBGUIXSA-N |
| Purity | >98% (HPLC) |
Lagerbedingungen
-20 C
Technische Merkmale
- Nucleobase
- Adenine
- Sugar
- 2'-Deoxyribose
- Base substituent
- 8-Bromo
- Conformational context
- 8-Substituted purine; syn-favoring
- Packaging
- 100 mg; 500 mg; 1 g; 5 g; 10 umol (~3.3 mg); 5 x 10 umol; Custom packaging on request
Anwendungskontext
- syn-Conformation research: the cited literature discusses 8-substituted purines as systems with defined syn/anti glycosidic conformational behavior.
- C8-functionalization studies: the C8 bromine marks a chemically addressable position on the adenine base for modified-DNA and nucleoside research.
- Base-analog reference: CH64067 provides the 8-bromo-2'-deoxyadenosine identity for nucleoside chemistry research.
Zugehörige technische Ressourcen
Öffentliche Quellen
- Sustainability Challenges and Opportunities in Oligonucleotide Manufacturing
Journal of Organic Chemistry, 2021
Product-family technical context
- Solid-phase supports for oligonucleotide synthesis
Current Protocols in Nucleic Acid Chemistry, 2013
Product-family technical context
- Deoxynucleoside phosphoramidites—A new class of key intermediates for deoxypolynucleotide synthesis
Tetrahedron Letters, 1981
Product-family technical context
- Synthesis of deoxyoligonucleotides on a polymer support
Journal of the American Chemical Society, 1981
Product-family technical context
- PubChem-Verbindung 96547
PubChem · CID 96547
Häufig gestellte Fragen
How does it differ from 2'-deoxyadenosine?
It carries a bromine at the C8 position of adenine, whereas 2'-deoxyadenosine is unsubstituted. 2'-deoxyadenosine is cataloged separately.
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