8-Thioguanosine
Oligonucleotide Synthesis, RNA Raw Materials & Modification
Produktübersicht
Kurzüberblick
- Produktfamilie
- Oligonucleotide Synthesis, RNA Raw Materials & Modification
- MF
- C10H13N5O5S
- MW
- 315.31
- Reinheit
- 98.0%
8-Thioguanosine (8-mercaptoguanosine) is guanosine bearing a thiol/thioxo group at the C8 position of guanine. CH64069 is identified by CAS 26001-38-7, molecular formula C10H13N5O5S, molecular weight 315.31, PubChem CID 135457302, and InChIKey KZELNMSPWPFAEB-UMMCILCDSA-N.
The cited literature discusses bulky C8 substitution in purine nucleosides and nucleotides in relation to syn glycosidic conformation. CH64069 provides the 8-thioguanosine identity for base-analog, bulky-C8 purine, and nucleoside chemistry research.
Synonyme
8-Thioguanosine; 8-mercaptoguanosine; 8-MGuo
Identität und Spezifikationen
| Catalog No. | CH64069 |
| CAS No. | 26001-38-7 |
| Molecular Formula | C10H13N5O5S |
| Molecular Weight | 315.31 |
| PubChem CID | 135457302 |
| InChIKey | KZELNMSPWPFAEB-UMMCILCDSA-N |
| Purity | 98.0% |
Lagerbedingungen
-20 C
Technische Merkmale
- Nucleobase
- Guanine
- Sugar
- D-Ribose
- Base modification
- 8-Thio (8-mercapto)
- Conformational context
- 8-Substituted purine; syn-favoring
- Packaging
- 50 mg; 100 mg; 250 mg; 500 mg; Custom packaging on request
- Physical form
- white crystalline solid
- Stability
- In solution: 6 months at -80 C or 1 month at -20 C
Anwendungskontext
- 8-Substituted purine research: CH64069 is a C8-thio guanosine analog for bulky-C8 purine and syn/anti glycosidic conformation research contexts.
- Base-analog reference: CH64069 provides the 8-thioguanosine identity for nucleoside chemistry research.
Zugehörige technische Ressourcen
Öffentliche Quellen
- Sustainability Challenges and Opportunities in Oligonucleotide Manufacturing
Journal of Organic Chemistry, 2021
Product-family technical context
- Solid-phase supports for oligonucleotide synthesis
Current Protocols in Nucleic Acid Chemistry, 2013
Product-family technical context
- Deoxynucleoside phosphoramidites—A new class of key intermediates for deoxypolynucleotide synthesis
Tetrahedron Letters, 1981
Product-family technical context
- Synthesis of deoxyoligonucleotides on a polymer support
Journal of the American Chemical Society, 1981
Product-family technical context
- PubChem-Verbindung 135457302
PubChem · CID 135457302
Häufig gestellte Fragen
What kind of modification does 8-thioguanosine carry?
It has a thiol/thioxo (mercapto) group at the C8 position of guanine, making it an 8-substituted bulky-C8 purine nucleoside.
How does it differ from guanosine?
It carries a C8-thio group, whereas guanosine is unsubstituted. Guanosine is cataloged separately.
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