CHEMOS
Oligonucleotide Synthesis, RNA Raw Materials & Modification

8-Hydroxy-2'-deoxyguanosine

Oligonucleotide Synthesis, RNA Raw Materials & Modification

Produkt-Nr.CH64071CAS-Nr.88847-89-6Reinheit>=98%
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Produktübersicht

Kurzüberblick

Produktfamilie
Oligonucleotide Synthesis, RNA Raw Materials & Modification
MF
C10H13N5O5
MW
283.24
Reinheit
>=98%

8-Hydroxy-2'-deoxyguanosine (8-oxo-dG) is the C8-oxidized form of 2'-deoxyguanosine. CH64071 is identified by CAS 88847-89-6, molecular formula C10H13N5O5, molecular weight 283.24, PubChem CID 135440064, and InChIKey HCAJQHYUCKICQH-VPENINKCSA-N.

The cited oxidative-stress literature discusses 8-hydroxy-2'-deoxyguanosine as a form of oxidative DNA damage and a marker of cellular oxidative stress. CH64071 provides the 8-oxo-dG identity for oxidative DNA damage, oxidized nucleoside, and nucleoside chemistry research.

Synonyme

8-Hydroxy-2'-deoxyguanosine; 8-oxo-dG; 8-oxo-2'-deoxyguanosine; 8-OHdG

Identität und Spezifikationen

Catalog No.CH64071
CAS No.88847-89-6
Molecular FormulaC10H13N5O5
Molecular Weight283.24
PubChem CID135440064
InChIKeyHCAJQHYUCKICQH-VPENINKCSA-N
Purity>=98%

Lagerbedingungen

-20 C

Technische Merkmale

Nucleobase
Oxidized guanine
Sugar
2'-Deoxyribose
Base modification
8-Hydroxy / 8-oxo
Research role
Oxidative-DNA-damage nucleoside reference
Grade
for Biochemistry
Packaging
5 mg; 5 umol (~1.5 mg); 5 x 5 umol; Custom packaging on request
Physical form
crystalline solid
Stability
>=4 years

Anwendungskontext

  • Oxidative-DNA-damage marker research: the cited literature discusses 8-oxo-dG as a form of oxidative DNA damage and a marker of cellular oxidative stress.
  • Oxidized nucleoside reference: CH64071 provides the 8-hydroxy-2'-deoxyguanosine identity for oxidized nucleoside and nucleoside chemistry research.

Zugehörige technische Ressourcen

Oligonukleotid-Modifikation

Zucker-, Basen-, Backbone-, terminale und Konjugationsmodifikationen für ASO, siRNA, guide RNA, Aptamere und Oligos.

Oligonukleotid-Synthese

Support für modifizierte Monomere, Supports, Sulfurisierungsreagenzien, Cap-Analoga und verwandte Oligo-Syntheseinputs.

Öffentliche Quellen

Häufig gestellte Fragen

How does it differ from 2'-deoxyguanosine?

It is the C8-oxidized (8-oxo/8-hydroxy) form of 2'-deoxyguanosine, whereas 2'-deoxyguanosine is unmodified. 2'-deoxyguanosine is cataloged separately.

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