N6-Methyl-2'-deoxyadenosine
Oligonucleotide Synthesis, RNA Raw Materials & Modification
Produktübersicht
Kurzüberblick
- Produktfamilie
- Oligonucleotide Synthesis, RNA Raw Materials & Modification
- MF
- C11H15N5O3
- MW
- 265.27
- Reinheit
- >=99.0% (HPLC)
N6-Methyl-2'-deoxyadenosine is 2'-deoxyadenosine methylated at the adenine N6 position, corresponding to the nucleoside form of DNA N6-methyladenine (6mA). CH64079 is identified by CAS 2002-35-9, molecular formula C11H15N5O3, molecular weight 265.27, PubChem CID 168948, and InChIKey DYSDOYRQWBDGQQ-XLPZGREQSA-N.
The cited literature discusses DNA N6-methyladenine (6mA) as an adenine-methylation epigenetic modification. Unlike acyl-protected building blocks, the N6-methyl group is a permanent base modification, not a removable protecting group.
Synonyme
N6-Methyl-2'-deoxyadenosine; N6-Me-dA; 6mA nucleoside; N6-methyl-dA
Identität und Spezifikationen
| Catalog No. | CH64079 |
| CAS No. | 2002-35-9 |
| Molecular Formula | C11H15N5O3 |
| Molecular Weight | 265.27 |
| PubChem CID | 168948 |
| InChIKey | DYSDOYRQWBDGQQ-XLPZGREQSA-N |
| Purity | >=99.0% (HPLC) |
Lagerbedingungen
-20 C
Technische Merkmale
- Nucleobase
- Adenine
- Sugar
- 2'-Deoxyribose
- Base modification
- N6-Methyl (6mA)
- Research role
- DNA epigenetic-mark nucleoside reference
- Packaging
- 25 mg; 100 mg; Custom packaging on request
- Water content
- <=5.0% KF
- Physical form
- white powder
- Stability
- >=4 years
Anwendungskontext
- 6mA epigenetic-mark research: CH64079 is the nucleoside form of DNA N6-methyladenine (6mA), an adenine-methylation epigenetic modification discussed in the cited literature.
- Base-modified nucleoside reference: CH64079 provides the N6-methyl-2'-deoxyadenosine identity for nucleoside chemistry research.
Zugehörige technische Ressourcen
Öffentliche Quellen
- Sustainability Challenges and Opportunities in Oligonucleotide Manufacturing
Journal of Organic Chemistry, 2021
Product-family technical context
- Solid-phase supports for oligonucleotide synthesis
Current Protocols in Nucleic Acid Chemistry, 2013
Product-family technical context
- Deoxynucleoside phosphoramidites—A new class of key intermediates for deoxypolynucleotide synthesis
Tetrahedron Letters, 1981
Product-family technical context
- Synthesis of deoxyoligonucleotides on a polymer support
Journal of the American Chemical Society, 1981
Product-family technical context
- PubChem-Verbindung 168948
PubChem · CID 168948
Häufig gestellte Fragen
Is the N6-methyl group a protecting group?
No. Unlike the N6-acyl (benzoyl/acetyl) building blocks, the N6-methyl here is a permanent base modification — the nucleoside form of the DNA epigenetic mark N6-methyladenine (6mA) — not a group that is removed during deprotection.
What is 6mA?
6mA (N6-methyladenine) is an adenine-methylation epigenetic modification in DNA. CH64079 is the corresponding N6-methyl-2'-deoxyadenosine nucleoside identity.
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