CHEMOS
Oligonucleotide Synthesis, RNA Raw Materials & Modification

N2-Phenoxyacetylguanosine

Oligonucleotide Synthesis, RNA Raw Materials & Modification

Produkt-Nr.CH64085CAS-Nr.119824-66-7Reinheit>=98%
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Produktübersicht

Kurzüberblick

Produktfamilie
Oligonucleotide Synthesis, RNA Raw Materials & Modification
MF
C18H19N5O7
MW
417.37
Reinheit
>=98%

N2-Phenoxyacetylguanosine (rG PAc) is guanosine whose guanine exocyclic N2-amine is protected with a phenoxyacetyl (PAc) group. CH64085 is identified by CAS 119824-66-7, molecular formula C18H19N5O7, molecular weight 417.37, PubChem CID 135921574, and InChIKey FOOYAXZEBFXEJD-IWCJZZDYSA-N.

The cited oligonucleotide-synthesis literature discusses labile exocyclic-amine protecting groups on nucleobases and their removal during deprotection. CH64085 provides the N2-phenoxyacetyl-protected guanosine identity for RNA building-block and nucleoside chemistry research.

Synonyme

N2-Phenoxyacetylguanosine; N2-PAc-rG; rG(PAc)

Identität und Spezifikationen

Catalog No.CH64085
CAS No.119824-66-7
Molecular FormulaC18H19N5O7
Molecular Weight417.37
PubChem CID135921574
InChIKeyFOOYAXZEBFXEJD-IWCJZZDYSA-N
Purity>=98%

Technische Merkmale

Nucleobase
Guanine
Sugar
D-Ribose
Base protection
N2-Phenoxyacetyl (PAc)
Synthesis role
Base-protected RNA nucleoside intermediate
Packaging
5 mg; 10 mg; 25 mg; 50 mg; 100 mg; 500 mg; 1 g; 5 g; 25 g; 100 g; Custom packaging on request

Anwendungskontext

  • Base-protected RNA building block: the N2-phenoxyacetyl (PAc) group masks the guanine exocyclic amine in RNA oligonucleotide-synthesis chemistry and is removed during deprotection.
  • Guanosine (rG) monomer precursor context: CH64085 is the PAc-protected guanosine identity relevant to guanine building-block preparation.
  • Nucleoside chemistry reference: CH64085 provides the N2-phenoxyacetylguanosine (rG PAc) identity for nucleoside chemistry research.

Zugehörige technische Ressourcen

Oligonukleotid-Modifikation

Zucker-, Basen-, Backbone-, terminale und Konjugationsmodifikationen für ASO, siRNA, guide RNA, Aptamere und Oligos.

Oligonukleotid-Synthese

Support für modifizierte Monomere, Supports, Sulfurisierungsreagenzien, Cap-Analoga und verwandte Oligo-Syntheseinputs.

Öffentliche Quellen

Häufig gestellte Fragen

What is the 'PAc' group on this guanosine?

PAc is phenoxyacetyl. In CH64085, the group is on the guanine exocyclic N2-amine and is part of the base-protected guanosine identity.

How does it differ from N2-isobutyrylguanosine?

Both protect the guanine N2-amine, but this one uses a phenoxyacetyl (PAc) group rather than isobutyryl. N2-isobutyrylguanosine is cataloged separately.

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