CHEMOS
Oligonucleotide Synthesis, RNA Raw Materials & Modification

N4-Benzoyl-2'-fluoro-2'-deoxycytidine

Oligonucleotide Synthesis, RNA Raw Materials & Modification

Produkt-Nr.CH64092CAS-Nr.146954-76-9Reinheit>=98.0% (HPLC)
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Produktübersicht

Kurzüberblick

Produktfamilie
Oligonucleotide Synthesis, RNA Raw Materials & Modification
MF
C16H16FN3O5
MW
349.31
Reinheit
>=98.0% (HPLC)

N4-Benzoyl-2'-fluoro-2'-deoxycytidine is 2'-fluoro-2'-deoxycytidine whose cytosine exocyclic N4-amine is protected with a benzoyl group. CH64092 is identified by CAS 146954-76-9, molecular formula C16H16FN3O5, molecular weight 349.31, PubChem CID 54266478, and InChIKey RHCOKFXBQWNMHE-BPGGGUHBSA-N.

The cited oligonucleotide-synthesis literature discusses exocyclic-amine protecting groups and their removal during deprotection. The cited oligonucleotide literature discusses 2'-fluoro modifications in relation to RNA affinity and nuclease resistance.

Synonyme

N4-Benzoyl-2'-fluoro-2'-deoxycytidine; N4-Bz-2'-F-dC; 2'-F-rC(Bz)

Identität und Spezifikationen

Catalog No.CH64092
CAS No.146954-76-9
Molecular FormulaC16H16FN3O5
Molecular Weight349.31
PubChem CID54266478
InChIKeyRHCOKFXBQWNMHE-BPGGGUHBSA-N
Purity>=98.0% (HPLC)

Lagerbedingungen

2-8 C; keep dark and dry

Technische Merkmale

Nucleobase
Cytosine
Sugar modification
2'-Fluoro-2'-deoxy
Base protection
N4-Benzoyl
Synthesis role
Base-protected 2'-fluoro nucleoside intermediate
Packaging
Custom packaging on request
Water content
<=2.0%
Physical form
white powder

Anwendungskontext

  • Base-protected 2'-F building block: the N4-benzoyl group masks the cytosine exocyclic amine in oligonucleotide-synthesis chemistry and is removed during deprotection.
  • 2'-Fluoro sugar modification context: cited oligonucleotide literature discusses 2'-fluoro modifications in relation to RNA affinity and nuclease resistance.
  • Nucleoside chemistry identity: a defined N4-benzoyl-2'-fluoro-2'-deoxycytidine compound for nucleoside chemistry research.

Zugehörige technische Ressourcen

Oligonukleotid-Modifikation

Zucker-, Basen-, Backbone-, terminale und Konjugationsmodifikationen für ASO, siRNA, guide RNA, Aptamere und Oligos.

Oligonukleotid-Synthese

Support für modifizierte Monomere, Supports, Sulfurisierungsreagenzien, Cap-Analoga und verwandte Oligo-Syntheseinputs.

Öffentliche Quellen

Häufig gestellte Fragen

How does it differ from N4-benzoyl-2'-O-methylcytidine?

Both are N4-benzoyl base-protected cytidines, but this one has a 2'-fluoro sugar modification rather than 2'-O-methyl. The 2'-OMe form is cataloged separately.

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