dATP, 100 mM Solution
Oligonucleotide Synthesis, RNA Raw Materials & Modification
Produktübersicht
Kurzüberblick
- Produktfamilie
- Oligonucleotide Synthesis, RNA Raw Materials & Modification
- MF
- C10H13N5Na3O12P3
- MW
- 557.13
- Reinheit
- 99.98%
dATP, 100 mM Solution is 2'-deoxyadenosine-5'-triphosphate (dATP) listed as a 100 mM aqueous solution of the trisodium salt. Key identifiers include CAS 54680-12-5, molecular formula C10H13N5Na3O12P3, and molecular weight 557.13 (PubChem CID 71650350).
dATP is one of the four canonical deoxynucleoside triphosphates (dNTPs). DNA polymerases catalyze the template-directed polymerization of dNTP substrates onto the 3'-end of a growing DNA primer strand, so dATP supplies the adenine (A) residue during enzymatic DNA synthesis — for example in PCR, primer extension, DNA sequencing, and nick translation.
Synonyme
2'-deoxyadenosine 5'-triphosphate trisodium salt; dATP·3Na, 100 mM aqueous solution
Identität und Spezifikationen
| Catalog No. | CH66001 |
| CAS No. | 54680-12-5 |
| Molecular Formula | C10H13N5Na3O12P3 (trisodium salt) |
| Molecular Weight | 557.13 |
| PubChem CID | 71650350 |
| InChIKey | VEESQMCFNINIMU-PWDLANNDSA-K |
| Concentration | 100 mM aqueous solution |
| Purity | 99.98% |
Lagerbedingungen
-20 C; avoid freeze-thaw cycles and frequent temperature changes
Technische Merkmale
- Nucleotide class
- dNTP
- Nucleobase
- Adenine
- 5'-phosphate state
- Triphosphate
- Grade
- PCR Grade
- Packaging
- 100 µL; 1 mL; 5 mL; 10 mL; 50 mL; Custom packaging on request
- Solution concentration
- 100 mM +/- 3
- Physical form
- clear colorless solution
- Stability
- 2 years
Anwendungskontext
- Adenine dNTP substrate: supplies the adenine (A) residue during enzymatic, template-directed DNA synthesis by DNA polymerases.
- Common reactions: PCR, primer extension, DNA sequencing, nick translation, and other polymerase-based DNA synthesis reactions.
- Solution presentation: listed as a 100 mM aqueous solution of the trisodium salt.
Zugehörige technische Ressourcen
Öffentliche Quellen
- Sustainability Challenges and Opportunities in Oligonucleotide Manufacturing
Journal of Organic Chemistry, 2021
Product-family technical context
- Solid-phase supports for oligonucleotide synthesis
Current Protocols in Nucleic Acid Chemistry, 2013
Product-family technical context
- Deoxynucleoside phosphoramidites—A new class of key intermediates for deoxypolynucleotide synthesis
Tetrahedron Letters, 1981
Product-family technical context
- Synthesis of deoxyoligonucleotides on a polymer support
Journal of the American Chemical Society, 1981
Product-family technical context
- PubChem-Verbindung 71650350
PubChem · CID 71650350
Häufig gestellte Fragen
What is dATP used for?
dATP is the adenine deoxynucleoside triphosphate. DNA polymerases use it as a substrate to add adenine (A) residues during enzymatic, template-directed DNA synthesis — for example in PCR, primer extension, sequencing, and nick translation.
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