2'-FANA-cytidine
4-amino-1-[(2R,3S,4R,5R)-3-fluoro-4-hydroxy-5-(hydroxymethyl)oxolan-2-yl]pyrimidin-2-one
Produktübersicht
Kurzüberblick
- Produktfamilie
- Oligonucleotide Synthesis, RNA Raw Materials & Modification
- Chemischer Name
- 4-amino-1-[(2R,3S,4R,5R)-3-fluoro-4-hydroxy-5-(hydroxymethyl)oxolan-2-yl]pyrimidin-2-one
- MF
- C9H12FN3O4
- MW
- 245.21
- Reinheit
- >=98%
2'-FANA-cytidine is a 2'F-ANA modified nucleoside: cytidine attached to a 2'-deoxy-2'-fluoro-beta-D-arabinofuranose sugar. Key identifiers include CAS 56632-83-8, molecular formula C9H12FN3O4, molecular weight 245.21, and PubChem CID 151382.
The 2'F-ANA family uses an arabino C2' configuration, which distinguishes it from ribo 2'-F-RNA. CH70038 should be presented as a modified nucleoside/reference compound for structure and catalog matching, not as a protected CE phosphoramidite monomer.
Synonyme
2'-deoxy-2'-fluoro-arabino cytidine; 2'F-ANA cytidine
Identität und Spezifikationen
| Catalog No. | CH70038 |
| CAS No. | 56632-83-8 |
| Molecular Formula | C9H12FN3O4 |
| Molecular Weight | 245.21 |
| Exact Mass | 245.08118403 |
| PubChem CID | 151382 |
| InChIKey | NVZFZMCNALTPBY-PXBUCIJWSA-N |
| Purity | >=98% |
Lagerbedingungen
-20 C for powder; -80 C in solvent
Technische Merkmale
- Material class
- 2'F-ANA nucleoside
- Nucleobase
- Cytosine
- Sugar configuration
- 2'-Deoxy-2'-fluoro-beta-D-arabinofuranose
- Protection state
- Unprotected
- Grade
- Research Chemical; reference standard for [18F]FAC
- Packaging
- 2 mg; 5 mg; 10 mg; 25 mg; 50 mg; 100 mg; 250 mg; 10 mM, 1 mL; Custom packaging on request
- Solution concentration
- 10 mM; solvent not stated
- Physical form
- Solid
- Stability
- 3 years at -20 C for powder; 1 year at -80 C in solvent
Anwendungskontext
- 2'F-ANA nucleoside reference: a cytidine-bearing 2'-deoxy-2'-fluoroarabino nucleoside for modified-nucleic-acid research.
- Arabino 2'-fluoro chemistry: the arabino C2' configuration distinguishes 2'F-ANA nucleosides from ribo 2'-F-RNA analogues.
- Oligonucleotide chemistry context: use the 2'F-ANA class name and identifiers when matching research catalog records or confirmed internal specifications.
Zugehörige technische Ressourcen
Öffentliche Quellen
- Sustainability Challenges and Opportunities in Oligonucleotide Manufacturing
Journal of Organic Chemistry, 2021
Product-family technical context
- Solid-phase supports for oligonucleotide synthesis
Current Protocols in Nucleic Acid Chemistry, 2013
Product-family technical context
- Deoxynucleoside phosphoramidites—A new class of key intermediates for deoxypolynucleotide synthesis
Tetrahedron Letters, 1981
Product-family technical context
- Synthesis of deoxyoligonucleotides on a polymer support
Journal of the American Chemical Society, 1981
Product-family technical context
- PubChem-Verbindung 151382
PubChem · CID 151382
Häufig gestellte Fragen
What is 2'-FANA-cytidine?
2'-FANA-cytidine is a 2'-deoxy-2'-fluoroarabino cytidine modified nucleoside. Its cytidine base and arabino-configured 2'-fluoro sugar are confirmed by PubChem CID 151382.
How is 2'F-ANA different from ribo 2'-F-RNA?
Both contain a 2'-fluoro sugar modification, but 2'F-ANA has the arabino configuration at C2'. That stereochemical difference distinguishes 2'F-ANA nucleosides from ribo 2'-F-RNA analogues.
Is CH70038 a phosphoramidite monomer?
No. CH70038 is documented as the modified nucleoside 2'-FANA-cytidine. A protected CE phosphoramidite would require separate structural evidence and identifiers.
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