2'-FANA-Inosine
Oligonucleotide Synthesis, RNA Raw Materials & Modification
Produktübersicht
Kurzüberblick
- Produktfamilie
- Oligonucleotide Synthesis, RNA Raw Materials & Modification
- MF
- C10H11FN4O4
- MW
- 270.22
- Reinheit
- >=98%
2'-FANA-Inosine is a 2'F-ANA modified nucleoside: inosine (hypoxanthine base) attached to a 2'-deoxy-2'-fluoro-beta-D-arabinofuranose sugar. Key identifiers include CAS 98983-40-5, molecular formula C10H11FN4O4, and molecular weight 270.22 (PubChem CID 135778987).
The 2'F-ANA family uses an arabino C2' configuration, which distinguishes it from ribo 2'-F-RNA. CH70040 should be presented as a modified nucleoside/reference compound for structure and catalog matching, not as a protected CE phosphoramidite monomer.
Synonyme
2'-deoxy-2'-fluoroarabino inosine; 2'-deoxy-2'-fluoro-beta-D-arabinofuranosyl inosine
Identität und Spezifikationen
| Catalog No. | CH70040 |
| CAS No. | 98983-40-5 |
| Molecular Formula | C10H11FN4O4 |
| Molecular Weight | 270.22 |
| PubChem CID | 135778987 |
| InChIKey | NRVOTDBYJXFINS-GQTRHBFLSA-N |
| Purity | >=98% |
Lagerbedingungen
4 C under nitrogen; -80 C or -20 C in solvent under nitrogen
Technische Merkmale
- Material class
- 2'F-ANA nucleoside
- Nucleobase
- Hypoxanthine
- Sugar configuration
- 2'-Deoxy-2'-fluoro-beta-D-arabinofuranose
- Protection state
- Unprotected
- Packaging
- 5 mg; 10 mg; 25 mg; 50 mg; 100 mg; 200 mg; 250 mg; 500 mg; 1 g; Custom packaging on request
- Physical form
- White to off-white solid
- Stability
- 6 months at -80 C or 1 month at -20 C in solvent
Anwendungskontext
- 2'F-ANA nucleoside reference: a hypoxanthine-bearing 2'-deoxy-2'-fluoroarabino nucleoside for modified-nucleic-acid research.
- Arabino 2'-fluoro chemistry: the arabino C2' configuration distinguishes 2'F-ANA nucleosides from ribo 2'-F-RNA analogues.
- Oligonucleotide chemistry context: use the 2'F-ANA class name and identifiers when matching research catalog records or confirmed internal specifications.
Zugehörige technische Ressourcen
Öffentliche Quellen
- Sustainability Challenges and Opportunities in Oligonucleotide Manufacturing
Journal of Organic Chemistry, 2021
Product-family technical context
- Solid-phase supports for oligonucleotide synthesis
Current Protocols in Nucleic Acid Chemistry, 2013
Product-family technical context
- Deoxynucleoside phosphoramidites—A new class of key intermediates for deoxypolynucleotide synthesis
Tetrahedron Letters, 1981
Product-family technical context
- Synthesis of deoxyoligonucleotides on a polymer support
Journal of the American Chemical Society, 1981
Product-family technical context
- PubChem-Verbindung 135778987
PubChem · CID 135778987
Häufig gestellte Fragen
What is 2'-FANA-Inosine?
2'-FANA-Inosine is a 2'-deoxy-2'-fluoroarabino inosine modified nucleoside. Its hypoxanthine base and arabino-configured 2'-fluoro sugar are confirmed by PubChem CID 135778987.
How is 2'F-ANA different from ribo 2'-F-RNA?
Both contain a 2'-fluoro sugar modification, but 2'F-ANA has the arabino configuration at C2'. That stereochemical difference distinguishes 2'F-ANA nucleosides from ribo 2'-F-RNA analogues.
Is CH70040 a phosphoramidite monomer?
No. CH70040 is documented as the modified nucleoside 2'-FANA-Inosine. A protected CE phosphoramidite would require separate structural evidence and identifiers.
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