DMPE
DMPE
Résumé du produit
Aperçu rapide
- Famille de produits
- LNP & Nucleic Acid Delivery Lipids
- Nom chimique
- DMPE
- FM
- C33H66NO8P
- PM
- 635.85
DMPE is 1,2-Dimyristoyl-sn-glycero-3-phosphoethanolamine, a C14:0 phosphatidylethanolamine identified by CAS 998-07-2.
PubChem CID 9852308 and ChemicalBook both list the formula C33H66NO8P, molecular weight about 635.9, and InChIKey NEZDNQCXEZDCBI-WJOKGBTCSA-N for this identity.
This product is handled as DMPE, not DOPE; DOPE corresponds to a different phospholipid record.
Identité et spécifications
| Catalog No. | CH51031 |
| CAS No. | 998-07-2 |
| Chemical Name | DMPE |
| Full Name | 1,2-Dimyristoyl-sn-glycero-3-phosphoethanolamine |
| Synonyms | PE(14:0/14:0); dimyristoyl phosphatidylethanolamine; dimyristoyl cephalin; GPEtn(14:0/14:0) |
| Molecular Formula | C33H66NO8P |
| Molecular Weight | 635.85 |
| PubChem CID | 9852308 |
| InChIKey | NEZDNQCXEZDCBI-WJOKGBTCSA-N |
Contexte d’application
- Phosphatidylethanolamine identity work: supports matching DMPE, PE(14:0/14:0), and 1,2-Dimyristoyl-sn-glycero-3-phosphoethanolamine naming to CAS 998-07-2.
- Model membrane research: DMPE appears in literature involving phosphatidylethanolamine bilayers and synthetic membrane systems.
- Liposome and membrane biophysics studies: DMPE is represented in liposome and aminophospholipid interaction researchs.
Informations complémentaires sur le matériau
Caractéristiques
- Dimyristoyl phosphatidylethanolamine with 14:0 acyl chains at the sn-1 and sn-2 positions.
- Formula C33H66NO8P and molecular weight 635.85 in the catalog record.
- Distinct from DOPE, which is a different phosphatidylethanolamine identity.
Ressources techniques associées
Matériaux lipidiques pour vectorisation
Analogues de lipides ionisables, PEG-lipides, phospholipides, stérols et conjugués ligand-lipide pour la recherche.
Design de lipides ionisables
Définir les analogues par structure exacte, rôle de formulation, charge utile, voie expérimentale, hypothèse de dégradation et contrôles matière.
Sources publiques
- [(2R)-3-[2-aminoethoxy(hydroxy)phosphoryl]oxy-2-tetradecanoyloxypropyl] tetradecanoate | PubChem CID 9852308
- High-throughput in vivo screen of functional mRNA delivery identifies nanoparticles for endothelial cell gene editing
PNAS, 2018
Product-family technical context
- Selective organ targeting nanoparticles for tissue-specific mRNA delivery and CRISPR-Cas gene editing
Nature Nanotechnology, 2020
Product-family technical context
- Rational Design of Cationic Lipids for siRNA Delivery
Nature Biotechnology, 2010
Product-family technical context
- Biodegradable Lipids Enabling Rapidly Eliminated Lipid Nanoparticles for Systemic Delivery of RNAi Therapeutics
Molecular Therapy, 2013
Product-family technical context
Questions fréquentes
Is CH51031 DOPE?
No. The verified CAS identity is DMPE. DOPE is a different phosphatidylethanolamine record.
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