DOP-DEDA
DOP-DEDA
Résumé du produit
Aperçu rapide
- Famille de produits
- LNP & Nucleic Acid Delivery Lipids
- Nom chimique
- DOP-DEDA
- FM
- C43H83N2O8P
- PM
- 787.1
DOP-DEDA is a dioleoylglycerophosphate-diethylenediamine lipid derivative identified by CAS 2247753-10-0.
ChemicalBook lists the DOP-DEDA record with molecular formula C43H83N2O8P and molecular weight 787.1, matching the CHEMOS catalog molecular weight.
The product is presented here for charge-reversible and pH-responsive lipid nanoparticle research.
Identité et spécifications
| Catalog No. | CH51064 |
| CAS No. | 2247753-10-0 |
| Product Name | DOP-DEDA |
| Synonyms | Dioleoylglycerophosphate-diethylenediamine; 2-[(2-Aminoethyl)amino]ethyl (R)-2,3-bis(oleoyloxy)propyl hydrogen phosphate |
| Molecular Formula | C43H83N2O8P |
| Molecular Weight | 787.1 |
| Reference Source For Formula/MW | ChemicalBook / catalog representation |
Contexte d’application
- DOP-DEDA identity reference: connects the abbreviation DOP-DEDA with Dioleoylglycerophosphate-diethylenediamine and CAS 2247753-10-0.
- Charge-reversible lipid research: source literature reports DOP-DEDA in charge-reversible lipid nanoparticle studies.
- pH-responsive lipid systems: the published literature places DOP-DEDA in pH-responsive lipid nanoparticle research.
Informations complémentaires sur le matériau
Utilisations
DOP-DEDA is best described by its ChemicalBook identity, CAS 2247753-10-0, and formula C43H83N2O8P. Published literature describes charge-reversible and pH-responsive lipid nanoparticle systems involving this lipid.
Caractéristiques
- Dioleoyl phospholipid derivative with a diethylenediamine-containing headgroup.
- Formula C43H83N2O8P and molecular weight 787.1 follow the ChemicalBook DOP-DEDA record.
- Associated in the literature with charge-reversible and pH-responsive lipid nanoparticle research.
Ressources techniques associées
Matériaux lipidiques pour vectorisation
Analogues de lipides ionisables, PEG-lipides, phospholipides, stérols et conjugués ligand-lipide pour la recherche.
Design de lipides ionisables
Définir les analogues par structure exacte, rôle de formulation, charge utile, voie expérimentale, hypothèse de dégradation et contrôles matière.
Sources publiques
- High-throughput in vivo screen of functional mRNA delivery identifies nanoparticles for endothelial cell gene editing
PNAS, 2018
Product-family technical context
- Selective organ targeting nanoparticles for tissue-specific mRNA delivery and CRISPR-Cas gene editing
Nature Nanotechnology, 2020
Product-family technical context
- Rational Design of Cationic Lipids for siRNA Delivery
Nature Biotechnology, 2010
Product-family technical context
- Biodegradable Lipids Enabling Rapidly Eliminated Lipid Nanoparticles for Systemic Delivery of RNAi Therapeutics
Molecular Therapy, 2013
Product-family technical context
Questions fréquentes
Which names are associated with this compound?
Relevant names include DOP-DEDA, Dioleoylglycerophosphate-diethylenediamine, and 2-[(2-Aminoethyl)amino]ethyl (R)-2,3-bis(oleoyloxy)propyl hydrogen phosphate.
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