CHEMOS
Methyl 3-hydroxypropanoate

Methyl 3-hydroxypropanoate

Methyl 3-hydroxypropanoate•PROTAC
Structure: Methyl 3-hydroxypropanoate structure, CAS 6149-41-3, MW 104.1
N° produit
CH56008
CAS
6149-41-3
FM
C4H8O3
PM
104.1
Spécification
Catalog No.CH56008
CAS No.6149-41-3
Molecular FormulaC4H8O3
Molecular Weight104.1

CHEMOS Support for This Category

CHEMOS supports PROTAC building-block projects covering linkers, E3 ligase recruiter derivatives, and customized degrader intermediates. Linker building blocks : PEG acids, PEG azides, alkyl spacers, branched linkers, and rigid linkers. E3 recruiter derivatives : IMiD-related, VHL-related, and other recruiter building blocks for medicinal chemistry programs. Custom synthesis : linker design, functional-group installation, and intermediate preparation. Route and purification review : multi-step synthesis planning with attention to polarity, solubility, and impurity control. Scale-up evaluation : larger-batch preparation can be assessed after route feasibility review.

Vue d’ensemble

Methyl 3-hydroxypropanoate (CAS 6149-41-3, MF C4H8O3, MW 104.1) belongs to the PROTAC building-block class (linker / E3 ligand / warhead). Programs working with this compound typically focus on coupling-handle compatibility, linker length / composition exploration, and impurity control. Project scale-up and custom synthesis are coordinated by the CHEMOS R&D team across laboratory and production sites.

Applications

  • Methyl 3-hydroxypropanoate (6149-41-3) as a starting point for downstream chemistry programs
  • Reference material in targeted protein degradation chemistry programs
  • Bifunctional degrader synthesis with orthogonal protecting groups
  • Custom analog synthesis with controlled coupling handles

Besoin d’une synthèse à façon ?

Notre équipe CDMO accompagne la synthèse à façon, de l’évaluation de voie au développement de procédé et au scale-up.

Voir les services CDMO