Uridine
1-[(2R,3R,4S,5R)-3,4-dihydroxy-5-(hydroxymethyl)oxolan-2-yl]pyrimidine-2,4-dione
Résumé du produit
Aperçu rapide
- Famille de produits
- Oligonucleotide Synthesis, RNA Raw Materials & Modification
- Nom chimique
- 1-[(2R,3R,4S,5R)-3,4-dihydroxy-5-(hydroxymethyl)oxolan-2-yl]pyrimidine-2,4-dione
- FM
- C9H12N2O6
- PM
- 244.20
- Pureté
- 99.3% (HPLC)
Uridine is the canonical pyrimidine RNA nucleoside, with uracil linked to β-D-ribose. CH64012 is identified by CAS 58-96-8, molecular formula C9H12N2O6, molecular weight 244.20, and PubChem CID 6029. It is the ribose counterpart of 2'-deoxyuridine, which is cataloged separately as CH64005.
The supported research context is pyrimidine nucleoside phosphorylase enzymology and RNA nucleoside chemistry: uridine is a phosphorylase substrate and an unmodified pyrimidine ribonucleoside reference.
Synonymes
Uridine; uracil riboside; Urd
Identité et spécifications
| Catalog No. | CH64012 |
| CAS No. | 58-96-8 |
| Molecular Formula | C9H12N2O6 |
| Molecular Weight | 244.20 |
| PubChem CID | 6029 |
| InChIKey | DRTQHJPVMGBUCF-XVFCMESISA-N |
| Purity | 99.3% (HPLC) |
Conditions de stockage
Room temperature; cool and dark place below 15 C
Caractéristiques techniques
- Nucleobase
- Uracil
- Sugar
- D-Ribose
- Nucleoside class
- Pyrimidine ribonucleoside
- Packaging
- 5 g; 25 g; 100 g; Custom packaging on request
- Water content
- Karl Fischer result 0.17%
- Physical form
- Solid; white powder to crystal
- Stability
- >=4 years
Contexte d’application
- Nucleoside phosphorylase substrate: uridine is phosphorolyzed by pyrimidine nucleoside phosphorylases in enzymology research.
- Pyrimidine RNA nucleoside reference: CH64012 provides the unmodified uridine identity for RNA and nucleoside chemistry comparisons.
Ressources techniques associées
Sources publiques
- Sustainability Challenges and Opportunities in Oligonucleotide Manufacturing
Journal of Organic Chemistry, 2021
Product-family technical context
- Solid-phase supports for oligonucleotide synthesis
Current Protocols in Nucleic Acid Chemistry, 2013
Product-family technical context
- Deoxynucleoside phosphoramidites—A new class of key intermediates for deoxypolynucleotide synthesis
Tetrahedron Letters, 1981
Product-family technical context
- Synthesis of deoxyoligonucleotides on a polymer support
Journal of the American Chemical Society, 1981
Product-family technical context
- Composé PubChem 6029
PubChem · CID 6029
Questions fréquentes
Is CH64012 the RNA or DNA nucleoside?
It is uridine, the RNA (ribo) nucleoside. The DNA counterpart, 2'-deoxyuridine, is listed separately by CHEMOS.
How is uridine used in enzyme research?
Uridine is phosphorolyzed by pyrimidine (uridine) nucleoside phosphorylases, so it is used as a reference substrate in phosphorylase enzymology.
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