7-Deaza-2'-deoxyguanosine
Oligonucleotide Synthesis, RNA Raw Materials & Modification
Résumé du produit
Aperçu rapide
- Famille de produits
- Oligonucleotide Synthesis, RNA Raw Materials & Modification
- FM
- C11H14N4O4
- PM
- 266.25
- Pureté
- >=98.0%
7-Deaza-2'-deoxyguanosine (c7dG) is 2'-deoxyguanosine in which the purine N7 nitrogen is replaced by carbon, giving a pyrrolo[2,3-d]pyrimidine base. CH64046 is identified by CAS 86392-75-8, molecular formula C11H14N4O4, molecular weight 266.25, and PubChem CID 135411006.
The cited oligonucleotide literature discusses 7-deaza-dG analogs in base-pairing, duplex-stability, and sequencing band-compression studies where the purine N7 position is being evaluated.
Synonymes
7-Deaza-2'-deoxyguanosine; c7dG; 7-deaza-dG
Identité et spécifications
| Catalog No. | CH64046 |
| CAS No. | 86392-75-8 |
| Molecular Formula | C11H14N4O4 |
| Molecular Weight | 266.25 |
| PubChem CID | 135411006 |
| InChIKey | PFCLMNDDPTZJHQ-XLPZGREQSA-N |
| Purity | >=98.0% |
Conditions de stockage
2-8 C; keep dark and dry
Caractéristiques techniques
- Nucleobase analog
- 7-Deazaguanine
- Sugar
- 2'-Deoxyribose
- Base modification
- 7-Deaza (N7 replaced by carbon)
- Research role
- Modified-oligonucleotide building-block reference
- Packaging
- 100 mg; 250 mg; 1 g; 5 g; Custom packaging on request
- Physical form
- White to off-white powder
Contexte d’application
- 7-Deazapurine oligonucleotide research: CH64046 is relevant to base-pairing, duplex-stability, and sequencing band-compression studies involving the N7→C base modification.
- N7-position interaction studies: the 7-deaza base supports comparison of DNA systems where Hoogsteen contacts or metal-binding behavior at the purine N7 position is being evaluated.
- Base-analog reference: CH64046 provides the 7-deaza-2'-deoxyguanosine identity for nucleoside chemistry research.
Ressources techniques associées
Sources publiques
- Sustainability Challenges and Opportunities in Oligonucleotide Manufacturing
Journal of Organic Chemistry, 2021
Product-family technical context
- Solid-phase supports for oligonucleotide synthesis
Current Protocols in Nucleic Acid Chemistry, 2013
Product-family technical context
- Deoxynucleoside phosphoramidites—A new class of key intermediates for deoxypolynucleotide synthesis
Tetrahedron Letters, 1981
Product-family technical context
- Synthesis of deoxyoligonucleotides on a polymer support
Journal of the American Chemical Society, 1981
Product-family technical context
- Composé PubChem 135411006
PubChem · CID 135411006
Questions fréquentes
What is different about 7-deaza-2'-deoxyguanosine?
The purine N7 nitrogen is replaced by carbon, giving a 7-deazapurine base. This allows comparison of systems where the purine N7 position is relevant to Hoogsteen pairing, metal binding, or sequencing band compression.
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