8-Bromo-2'-deoxyguanosine
Oligonucleotide Synthesis, RNA Raw Materials & Modification
Résumé du produit
Aperçu rapide
- Famille de produits
- Oligonucleotide Synthesis, RNA Raw Materials & Modification
- FM
- C10H12BrN5O4
- PM
- 346.14
- Pureté
- >98% (HPLC)
8-Bromo-2'-deoxyguanosine is 2'-deoxyguanosine bearing a bromine at the C8 position of guanine. CH64065 is identified by CAS 13389-03-2, molecular formula C10H12BrN5O4, molecular weight 346.14, PubChem CID 135437126, and InChIKey MKDXZFVCXWXGBQ-VPENINKCSA-N.
The cited literature discusses 8-substituted purine nucleosides and nucleotides in relation to syn/anti glycosidic conformation, including 8-bromoguanine nucleosides. CH64065 provides the 8-bromo-2'-deoxyguanosine identity for modified-DNA, base-analog, and C8-functionalization research contexts.
Synonymes
8-Bromo-2'-deoxyguanosine; 8-Br-dG
Identité et spécifications
| Catalog No. | CH64065 |
| CAS No. | 13389-03-2 |
| Molecular Formula | C10H12BrN5O4 |
| Molecular Weight | 346.14 |
| PubChem CID | 135437126 |
| InChIKey | MKDXZFVCXWXGBQ-VPENINKCSA-N |
| Purity | >98% (HPLC) |
Conditions de stockage
-20 C
Caractéristiques techniques
- Nucleobase
- Guanine
- Sugar
- 2'-Deoxyribose
- Base substituent
- 8-Bromo
- Conformational context
- 8-Substituted purine; syn-favoring
- Packaging
- 100 mg; 1 g; 10 g; 25 g; 50 g; 10 umol (~3.5 mg); 5 x 10 umol; Custom packaging on request
- Physical form
- solid
- Stability
- Powder: 2 years; in solution: 6 months at -20 C or 1 year at -80 C
Contexte d’application
- syn-Conformation research: the cited literature discusses 8-substituted purines, including 8-bromoguanine nucleosides, as systems with defined syn/anti glycosidic conformational behavior.
- C8-functionalization studies: the C8 bromine marks a chemically addressable position on the guanine base for modified-DNA and nucleoside research.
- Base-analog reference: CH64065 provides the 8-bromo-2'-deoxyguanosine identity for nucleoside chemistry research.
Ressources techniques associées
Sources publiques
- Sustainability Challenges and Opportunities in Oligonucleotide Manufacturing
Journal of Organic Chemistry, 2021
Product-family technical context
- Solid-phase supports for oligonucleotide synthesis
Current Protocols in Nucleic Acid Chemistry, 2013
Product-family technical context
- Deoxynucleoside phosphoramidites—A new class of key intermediates for deoxypolynucleotide synthesis
Tetrahedron Letters, 1981
Product-family technical context
- Synthesis of deoxyoligonucleotides on a polymer support
Journal of the American Chemical Society, 1981
Product-family technical context
- Composé PubChem 135437126
PubChem · CID 135437126
Questions fréquentes
How does it differ from 2'-deoxyguanosine?
It carries a bromine at the C8 position of guanine, whereas 2'-deoxyguanosine is unsubstituted. 2'-deoxyguanosine is cataloged separately.
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