2'-FANA-guanosine
2-amino-9-[(2R,3S,4R,5R)-3-fluoro-4-hydroxy-5-(hydroxymethyl)oxolan-2-yl]-1H-purin-6-one
Résumé du produit
Aperçu rapide
- Famille de produits
- Oligonucleotide Synthesis, RNA Raw Materials & Modification
- Nom chimique
- 2-amino-9-[(2R,3S,4R,5R)-3-fluoro-4-hydroxy-5-(hydroxymethyl)oxolan-2-yl]-1H-purin-6-one
- FM
- C10H12FN5O4
- PM
- 285.23
- Pureté
- 99.45%
2'-FANA-guanosine is a 2'F-ANA modified nucleoside: guanosine attached to a 2'-deoxy-2'-fluoro-beta-D-arabinofuranose sugar. Key identifiers include CAS 103884-98-6, molecular formula C10H12FN5O4, molecular weight 285.23, and PubChem CID 135434940.
The 2'F-ANA family uses an arabino C2' configuration, which distinguishes it from ribo 2'-F-RNA. CH70039 should be presented as a modified nucleoside/reference compound for structure and catalog matching, not as a protected CE phosphoramidite monomer.
Synonymes
2'-deoxy-2'-fluoro-arabino guanosine; 2'F-ANA guanosine
Identité et spécifications
| Catalog No. | CH70039 |
| CAS No. | 103884-98-6 |
| Molecular Formula | C10H12FN5O4 |
| Molecular Weight | 285.23 |
| Exact Mass | 285.08733204 |
| PubChem CID | 135434940 |
| InChIKey | UXUZARPLRQRNNX-AYQXTPAHSA-N |
| Identity Note | PubChem maps CAS 103884-98-6 to multiple stereochemical records; this entry uses PubChem CID 135434940 for the FANA arabino configuration. |
| Purity | 99.45% |
Conditions de stockage
-20 C
Caractéristiques techniques
- Material class
- 2'F-ANA nucleoside
- Nucleobase
- Guanine
- Sugar configuration
- 2'-Deoxy-2'-fluoro-beta-D-arabinofuranose
- Protection state
- Unprotected
- Packaging
- 1 mg; 5 mg; 10 mg; 25 mg; 50 mg; 100 mg; 200 mg; 250 mg; 500 mg; 1 g; Custom packaging on request
- Physical form
- White to off-white powder to crystals
- Stability
- 3 years at -20 C for powder; 1 year at -80 C in solvent
Contexte d’application
- 2'F-ANA nucleoside reference: a guanosine-bearing 2'-deoxy-2'-fluoroarabino nucleoside for modified-nucleic-acid research.
- Arabino 2'-fluoro chemistry: the arabino C2' configuration distinguishes 2'F-ANA nucleosides from ribo 2'-F-RNA analogues.
- Oligonucleotide chemistry context: use the 2'F-ANA class name and verified identifiers when matching research catalog records or confirmed internal specifications.
Ressources techniques associées
Sources publiques
- Sustainability Challenges and Opportunities in Oligonucleotide Manufacturing
Journal of Organic Chemistry, 2021
Product-family technical context
- Solid-phase supports for oligonucleotide synthesis
Current Protocols in Nucleic Acid Chemistry, 2013
Product-family technical context
- Deoxynucleoside phosphoramidites—A new class of key intermediates for deoxypolynucleotide synthesis
Tetrahedron Letters, 1981
Product-family technical context
- Synthesis of deoxyoligonucleotides on a polymer support
Journal of the American Chemical Society, 1981
Product-family technical context
- Composé PubChem 135434940
PubChem · CID 135434940
Questions fréquentes
What is 2'-FANA-guanosine?
2'-FANA-guanosine is a 2'-deoxy-2'-fluoroarabino guanosine modified nucleoside. PubChem maps the CAS to multiple stereochemical records; this page uses CID 135434940 for the FANA arabino configuration.
How is 2'F-ANA different from ribo 2'-F-RNA?
Both contain a 2'-fluoro sugar modification, but 2'F-ANA has the arabino configuration at C2'. That stereochemical difference distinguishes 2'F-ANA nucleosides from ribo 2'-F-RNA analogues.
Is CH70039 a phosphoramidite monomer?
No. CH70039 is documented as the modified nucleoside 2'-FANA-guanosine. A protected CE phosphoramidite would require separate structural evidence and identifiers.
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