DSPE
化学名称
1,2-Distearoyl-sn-glycero-3-phosphorylethanolamine
DSPE•LNP
Structure: 
产品编号
CH51013
CAS
1069-79-0
分子式
C41H82NO8P
分子量
748.07
规格标准
| Catalog No. | CH51013 |
| CAS No. | 1069-79-0 |
| Molecular Formula | C41H82NO8P |
| Molecular Weight | 748.07 |
品类工艺支持
CHEMOS supports custom synthesis and process development for LNP lipid components, with work planned according to target structure, requested scale, and analytical requirements. Ionizable lipid route development : route scouting, impurity review, stereochemistry control, and purification planning. Helper lipid and PEG-lipid preparation : support for phospholipids, sterol-related components, PEG-lipids, and related analogs. Analytical support : HPLC, NMR, MS, Karl Fischer water content, elemental analysis, and residual-solvent testing can be discussed by project. Scale-up support : transfer from laboratory preparation to larger pilot or production batches after route and quality review. Project documentation : batch-specific COA and technical information are provided according to the confirmed specification.
概况
DSPE (also known as 1,2-Distearoyl-sn-glycero-3-phosphorylethanolamine) (CAS 1069-79-0, MF C41H82NO8P, MW 748.07) belongs to the helper phospholipid class used in nucleic acid delivery system research and liposomal drug carriers. Typical chemistry topics include stereo-purity at the glycerol backbone, residual free fatty acid, and related diacyl regio-isomers. CHEMOS process chemistry, organic synthesis routes and project scale-up support are offered for downstream programs.
应用
- DSPE (CAS 1069-79-0) route review and custom analog preparation
- Helper phospholipid component in LNP and liposomal formulation research
- Bilayer-property studies in nucleic-acid delivery system development
- Pulmonary surfactant and biophysical research applications