DSPE-MPEG2000
化学名称
sodium [(2R)-2,3-di(octadecanoyloxy)propyl] 2-(2-methoxyethoxycarbonylamino)ethyl phosphate
DSPE-MPEG2000•LNP
Structure: 
产品编号
CH51015
CAS
147867-65-0
分子式
C45H87NNaO11P
分子量
872.135911
规格标准
| Catalog No. | CH51015 |
| CAS No. | 147867-65-0 |
| Molecular Formula | C45H87NNaO11P |
| Molecular Weight | 872.135911 |
品类工艺支持
CHEMOS supports custom synthesis and process development for LNP lipid components, with work planned according to target structure, requested scale, and analytical requirements. Ionizable lipid route development : route scouting, impurity review, stereochemistry control, and purification planning. Helper lipid and PEG-lipid preparation : support for phospholipids, sterol-related components, PEG-lipids, and related analogs. Analytical support : HPLC, NMR, MS, Karl Fischer water content, elemental analysis, and residual-solvent testing can be discussed by project. Scale-up support : transfer from laboratory preparation to larger pilot or production batches after route and quality review. Project documentation : batch-specific COA and technical information are provided according to the confirmed specification.
概况
DSPE-MPEG2000 (also known as sodium [(2R)-2,3-di(octadecanoyloxy)propyl] 2-(2-methoxyethoxycarbonylamino)ethyl phosphate) (CAS 147867-65-0, MF C45H87NNaO11P, MW 872.135911) is a PEG-lipid conjugate used as a stealth or functional component in nucleic-acid delivery systems. Practical chemistry questions involve PEG repeat distribution, lipid anchor integrity, and terminal-group functionalisation strategy. Project scale-up and custom synthesis are coordinated by the CHEMOS R&D team across laboratory and production sites.
应用
- DSPE-MPEG2000 (CAS 147867-65-0) preparation, route refinement, and analytical-control planning
- Process-development support for scalable PEG-lipid preparation
- Analytical method development for PEG-lipid characterisation
- Stealth or functional PEG-lipid component in LNP / liposomal formulation research