DMG-PEG2000

DMG-PEG2000

DMG-PEG2000LNP
Structure: DMG-PEG2000 structure, CAS 160743-62-4, MW 2000 (Average)
产品编号
CH51016
CAS
160743-62-4
分子式
(C2H4O)nC32H62O5
分子量
2000 (Average)
规格标准
Catalog No.CH51016
CAS No.160743-62-4
Molecular Formula(C2H4O)nC32H62O5
Molecular Weight2000 (Average)

品类工艺支持

CHEMOS supports custom synthesis and process development for LNP lipid components, with work planned according to target structure, requested scale, and analytical requirements. Ionizable lipid route development : route scouting, impurity review, stereochemistry control, and purification planning. Helper lipid and PEG-lipid preparation : support for phospholipids, sterol-related components, PEG-lipids, and related analogs. Analytical support : HPLC, NMR, MS, Karl Fischer water content, elemental analysis, and residual-solvent testing can be discussed by project. Scale-up support : transfer from laboratory preparation to larger pilot or production batches after route and quality review. Project documentation : batch-specific COA and technical information are provided according to the confirmed specification.

概况

DMG-PEG2000 (CAS 160743-62-4, MF (C2H4O)nC32H62O5, MW 2000 (Average)) is a PEG-lipid conjugate used as a stealth or functional component in nucleic-acid delivery systems. Practical chemistry questions involve PEG repeat distribution, lipid anchor integrity, and terminal-group functionalisation strategy. Project scale-up and custom synthesis are coordinated by the CHEMOS R&D team across laboratory and production sites.

应用

  • DMG-PEG2000 (160743-62-4) as a starting point for downstream chemistry programs
  • Custom synthesis of PEG-lipid analogs with controlled molecular weight
  • Analytical method development for PEG-lipid characterisation
  • PEG length and lipid-anchor variation studies for nucleic-acid delivery

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