ALC-0159
ALC-0159•LNP
Structure: 
产品编号
CH51027
CAS
1849616-42-7
分子式
(C2H4O)nC31H63NO2
分子量
Average MW not fixed by source
规格标准
| Catalog No. | CH51027 |
| CAS No. | 1849616-42-7 |
| Molecular Formula | (C2H4O)nC31H63NO2 |
| Molecular Weight | Average MW not fixed by source |
品类工艺支持
CHEMOS supports custom synthesis and process development for LNP lipid components, with work planned according to target structure, requested scale, and analytical requirements. Ionizable lipid route development : route scouting, impurity review, stereochemistry control, and purification planning. Helper lipid and PEG-lipid preparation : support for phospholipids, sterol-related components, PEG-lipids, and related analogs. Analytical support : HPLC, NMR, MS, Karl Fischer water content, elemental analysis, and residual-solvent testing can be discussed by project. Scale-up support : transfer from laboratory preparation to larger pilot or production batches after route and quality review. Project documentation : batch-specific COA and technical information are provided according to the confirmed specification.
概况
ALC-0159 (CAS 1849616-42-7, MF (C2H4O)nC31H63NO2, MW Average MW not fixed by source) is a PEGylated lipid used in LNP and liposomal formulations to control particle stability and circulation behaviour. Programs working with PEG-lipid materials typically examine PEG molecular-weight distribution, lipid anchor identity, and end-group chemistry. CHEMOS process chemistry, organic synthesis routes and project scale-up support are offered for downstream programs.
应用
- ALC-0159 (CAS 1849616-42-7) route review and custom analog preparation
- PEG length and lipid-anchor variation studies for nucleic-acid delivery
- Conjugation-handle PEG-lipid synthesis for downstream coupling chemistry
- Custom synthesis of PEG-lipid analogs with controlled molecular weight