DOTAP MeSO4
化学名称
DOTAP methyl sulfate
DOTAP MeSO4•LNP
Structure: 
产品编号
CH51042
CAS
144189-73-1
分子式
C43H83NO8S
分子量
774.19
规格标准
| Catalog No. | CH51042 |
| CAS No. | 144189-73-1 |
| Molecular Formula | C43H83NO8S |
| Molecular Weight | 774.19 |
品类工艺支持
CHEMOS supports custom synthesis and process development for LNP lipid components, with work planned according to target structure, requested scale, and analytical requirements. Ionizable lipid route development : route scouting, impurity review, stereochemistry control, and purification planning. Helper lipid and PEG-lipid preparation : support for phospholipids, sterol-related components, PEG-lipids, and related analogs. Analytical support : HPLC, NMR, MS, Karl Fischer water content, elemental analysis, and residual-solvent testing can be discussed by project. Scale-up support : transfer from laboratory preparation to larger pilot or production batches after route and quality review. Project documentation : batch-specific COA and technical information are provided according to the confirmed specification.
概况
DOTAP MeSO4 (also known as DOTAP methyl sulfate) (CAS 144189-73-1, MF C43H83NO8S, MW 774.19) is an ionizable lipid analog studied in lipid nanoparticle (LNP) formulations for nucleic acid delivery research, including mRNA and siRNA platforms. Practical chemistry topics around this compound include head-group structure, ester or amine linker chemistry, and tail unsaturation. CHEMOS process-development team and large production base can support route refinement, scale-up and custom synthesis on request.
应用
- DOTAP MeSO4 (144189-73-1) supply and analog preparation for research programs
- Custom analog synthesis with controlled head-group and tail variants
- Reference comparator in next-generation ionizable lipid programs
- Analytical method development for ionizable lipid related substances